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2017, Number 1

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Rev Cubana Pediatr 2017; 89 (1)

Appropriate indicated use for IVIG in neonatal infections

Wang Y, Ping LY, Yan YH, Wen XY, Ping X, Bo T

Language: English
References: 12
Page: 92-97
PDF size: 78.86 Kb.


ABSTRACT

Infection is a leading cause of mortality and morbidity in the newborn and preterm neonates due to immuno-incompetence in these patients. Administration of intravenous immunoglobulin (IVIG) provides immunoglobulin G (IgG) that can protect the body from infection. In theory, morbidity and mortality due to infections in newborns and preterm infants could be reduced by the administration of IVIG. Two meta-analyses were evaluated comparing IVIG to treat various infection versus conventional treatments. The results showed that IVIG is not effective as an adjunctive treatment for suspected or proven infections in neonates.


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