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2017, Number 4

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Rev Fac Med UNAM 2017; 60 (4)

Thyroid storm, an endocrine emergency. Case report and literature review

Mercado CE, García CCF, Arellano TA, Rodríguez HA
Full text How to cite this article

Language: Spanish
References: 12
Page: 27-36
PDF size: 286.93 Kb.


Key words:

Thyroid storm, thyrotoxicosis, hyperthyroidism.

ABSTRACT

The thyroid storm is a critical and rare disease, which conditions the dysfunction of multiple organs due to the excessive effect of thyroid hormones. This endocrine dysfunction has a high mortality and generates typical manifestations such as tachycardia, fever, gastrointestinal alterations, and cardiovascular and neurological disorders.
The diagnosis is primarily clinical and can be supported by the scale of “Burch and Wartofsky”. Serum concentrations of thyroid hormones are not correlated with the severity of the symptoms, but their assessment is useful to confirm the diag nosis. Other tests that may help complement the diagnosis are thyroid ultrasound, cardiac markers, and assessment of liver and kidney function.
It is usually possible to identify a triggering factor, although in exceptional cases, the thyroid storm may also be the initial manifestation of some thyroid pathology.
Therapeutic strategies are aimed at inhibiting the synthesis and the release of thyroid hormones as well as reducing their concentration and peripheral effects, without forgetting the treatment of the triggering factor.


REFERENCES

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  2. Devereaux D, Tewelde SZ. Hyperthyroidism and yrotoxicosis. Emerg Med Clin North Am [Internet]. Elsevier Inc; 2014;32(2):277-92. [Citado: 31 de marzo de 2017]. Disponible en: http://www.ncbi.nlm.nih.gov/pubmed/ 24766932%0Ahttp://linkinghub.elsevier.com/retrieve/pii/ S0733862713001314

  3. Papi G, Corsello SM, Pontecorvi A. Clinical concepts on thyroid emergencies. Front Endocrinol (Lausanne). 2014; 5(jul):1-11.

  4. De Leo S, Lee SY, Braverman LE. Hyperthyroidism. 2016; 288:906-18.

  5. Klubo-Gwiezdzinska J, Wartofsky L. yroid Emergencies. Med Clin NA. 2012;96:385-403.

  6. Burch H, Wartofsky L. Life-threatening thyrotoxicosis. yroid storm. Endocrinol Metab Clin North Am. 1993; 22(2):263-77.

  7. Satoh T, Isozaki O, Suzuki A, Wakino S, Iburi T, Tsuboi K, et al. 2016 Guidelines for the management of thyroid storm from e Japan yroid Association and Japan Endocrine Society (First edition). Endocr J [Internet]. 2016;84(6):912-

  8. [Citado: 31 de marzo de 2017]. Disponible en: http:// www.ncbi.nlm.nih.gov/pubmed/27746415 8. Akamizu T, Satoh T, Isozaki O, Suzuki A, Wakino S, Iburi T, et al. Diagnostic Criteria, Clinical Features, and Incidence of yroid Storm Based on Nationwide Surveys. yroid. 2012;22(7):661-79.

  9. Mills L, Lim S. Identifying And Treating yroid Storm And Myxedema Coma In e Emergency. Emerg Med Pract. 2009;11(8):1-26.

  10. Mantilla D, Echin ML, Perel C. Hipertiroidismo y sistema cardiovascular. Bases fisiopatológicas y su manifestación clínica. Insufic Card. 2010;5(4):157-77.

  11. Surawicz B, Knilans T. Chou’s Electrocardiography in Clinical Practice. 6th Edition. Philadelphia, EUA: Saunders Elsevier Inc., editor. 2008. 752 p.

  12. Cooper D. Antithyroid drugs. N Engl J Med. 2005;352(21): 905-17.




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Rev Fac Med UNAM . 2017;60