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ISSN 1995-9494 (Electronic)
Revista del Hospital Clínico Quirúrgico "Arnaldo Milián Castro"

2017, Number 3

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Acta Med Cent 2017; 11 (3)

Vasculitis hipocomplementémica urticarial no dolorosa que debuta con astenia severa. Informe de caso

Vasquez-Bonilla WO, Hernandez-Hernandez HR, Trejo-Alvarez RE

Language: Spanish
References: 14
Page: 68-74
PDF size: 255.81 Kb.


ABSTRACT

Urticarial vasculitis is a clinicopathological disease characterized by recurrent episodes of urticaria and leukocytoclastic vasculitis in histopathology; in this work it is presented the variant hypocomplemotic vasculitic urticarial syndrome, which affects small vessels and it is associated with anti-C1q antibodies and it is characterized, mainly by non-pruriginous urticarial lesions of more than 24 hours of evolution (preferably in women in the fourth decade of life). It is presented a female patient of 33 years old who debuted with severe asthenia and dermatological lesions of maculopapular-type of annular morphology non-painful, non-pruriginous at the Medical Center Hospital in Tegucigalpa, Honduras, with a mean time of evolution to disease progression of 24 months. Serum samples were sent to laboratories in the United States of America to complete immunological studies and a biopsy sample of dermatological lesion was sent to the Quest Diagnostics Incorporated Nichols Institute f-r immunohistochemistry, which reported low complement vasculitis with positive immunohistochemical staining to anti-C1q antigen. The correct diagnosis of a vasculitic syndrome will depend on the exclusion of secondary causes through the proper use of the different diagnostic methods and a high clinical suspicion that guarantees the certainty of the diagnostic approach.


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