Rivas-de Noriega JP, Ontañon-Zurita D, Turrent-Carriles A

Language: Spanish
References: 5
Page: 522-525
PDF size: 168.49 Kb.

ABSTRACT

We report the case of a woman in the fourth decade of life with previous medical history of rheumatoid arthritis and vitiligo who presented with anemic syndrome. In the diagnostic workup we found low levels of vitamin B₁₂ and positive intrinsic factor antibodies that corroborate the diagnosis of pernicious anemia. This clinical case supports the definition of polyautoimmune syndrome in which there is a link between different autoimmune diseases without a previous known relation.

REFERENCES

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2. Littlewood TJ, Keel SB. Acquired underproduction anemias. American Society of Hematology Self-Assessment Program (ASH-SAP). 5th ed. Estados Unidos, 2013;115-118.

3. Zeev A, et al. Vitiligo, rheumatoid arthritis and pernicious anemia. J Dermatol 1993;20.

4. Rojas-Villarraga A, et al. Introducing polyautoimmunity: secondary autoimmune diseases no longer exist. Autoimmune Diseases 2012.

5. Cho JH, Feldman M. Heterogeneity of autoimmune diseases: pathophysiologic insights from genetics and implications for new therapies. Nature Medicine Reviews 2015;21.