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2001, Number 4

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Rev Hosp Jua Mex 2001; 68 (4)

Diagnóstico y tratamiento de la enfermedad de Alzheimer con clioquinol radiactivo

Skromne KG, Hidalgo RR, Alcántara E
Full text How to cite this article

Language: Spanish
References: 4
Page: 175-177
PDF size: 38.72 Kb.


Key words:

Alzheimer disease, radiactive clioquinol, diagnostic and treatment.

ABSTRACT

We labeled clioquinol with Iodine-131 and proved this new radiopharmaco in experimental animals with good results. Lately in 12 patients with Alzheimer’s disease we carried out scans of the brain with radiactive clioquinol and in two of them we produced radiolisis of the amyloid insoluble plaques in three months. Nobody of the patients presented adverse reactions in six months of clinical and laboratorial follow-up. We propose the new radiopharmaco and method with more statistic research for the diagnosis and treatment of Alzheimer’s disease.


REFERENCES

  1. Helmuth L. An antibiotic to treat Alzheimer’s. Science 2000; 290 (5495): 1273.

  2. Ashley Bush. Proc General Massachusetts Hospital Boston, USA. 2000; 22: 969.

  3. Alvarez CJ. Skromne-Kadlubik G, et al. Labell of DDD I- 131. J Inter Applied Isotopes. 1973; 24: 187.

  4. Skromne-Kadlubik G, Hidalgo RR. Sobre la elaboración de una vacuna con anticuerpos monoclonales para la enfermedad de Alzheimer. Rev Hosp Jua Mex 2000; 76 (1): 21.




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C?MO CITAR (Vancouver)

Rev Hosp Jua Mex. 2001;68