medigraphic.com
ISSN 0185-6014 (Print)
Órgano oficial de difusión de la Federación Mexicana de Patología Clínica, AC y de la Asociación Latinoamericana de Patología Clínica/Medicina de Laboratorio

2017, Number 3

<< Back Next >>

Rev Mex Patol Clin Med Lab 2017; 64 (3)

Serum ferritin in men donating blood and blood components in Cienfuegos, Cuba, 2017

Sánchez FP, Capote PM, Díaz AK, Sánchez BMJ, Pérez BC, Brito DDM

Language: Spanish
References: 13
Page: 120-124
PDF size: 288.92 Kb.


ABSTRACT

Introduction: Donors of whole blood and blood components are vulnerable to declining iron stores. Goals: To evaluate, through the serum ferritin quantification, the iron reserves and their relation to the estimated losses of serum iron and erythrocyte mass in different types of donors. Material and methods: A descriptive, observational study was performed on 98 men donating clustered blood in three groups: first-time and habitual whole blood donors, and apheresis plasma donors. Their serum ferritin concentration was quantified and losses of erythrocyte mass and serum iron were estimated. Ferritin values were compared for each group and related to estimated losses. Results: Whole blood first-time donors showed higher mean ferritin values than the rest of the individuals. One-tenth of the total plasma and repetitive blood donors had ferritin levels below the values considered normal. Repetitive blood donors can lose up to twice erythrocytes and iron compared with plasma donors. Conclusions: Impairments in iron stores are similar in habitual and plasma donors, despite differences in the estimated amount of mineral loss. Recommendation: To protocol additional tests in the selection of habitual blood and components donors to monitor subclinical states of iron deficiency.


REFERENCES

  1. Higgins T, Eckfeldt J, Barton JC, Doumas BT. Hemoglobin, iron, and bilirubin. In: Burtis CA, Ashwood ER, Bruns DE. Tietz textbook of clinical chemistry and molecular diagnostics. 5th ed. Missouri, EUA: Elsevier Saunders; 2012. pp. 985-1029.

  2. Forrellat-Barrios M. Diagnóstico de la deficiencia de hierro: aspectos esenciales. Revista cubana de hematología, inmunología y hemoterapia [revista en Internet]. 2017 [citado 2017 Oct 10]; 33 (2). Disponible en: http://www.revhematologia.sld.cu/index.php/hih/article/view/534

  3. Sánchez M, Vives JL. Métodos para el diagnóstico de la ferropenia y el exceso de hierro. En: Vives-Corrons JL, Aguilar i Bascompte JL. Manual de técnicas de laboratorio en hematología. Barcelona: España: Elsevier; 2014. pp. 390-433.

  4. Mantilla-Gutiérrez CY, Cardona-Arias JA. Meta-análisis: prevalencia de deficiencia de hierro en donantes de sangre repetitivos y asociación con sexo, 2001-2011. Rev Cubana Hematol Inmunol Hemoter. 2013; 29 (1): 59-72. Disponible en: http://scielo.sld.cu/scielo.php?script=sci_arttext&pid=S0864-02892013000100007&lng=es.

  5. Fischer T, Surikova I, Heesen E, Wilms G, Laitinen T, Taborski U. Loss of red cell mass in a plasmapheresis machine: effect of rinsing the disposable tubing with normal saline and reinfusion. Transfus Apher Sci. 2013; 49 (1): 80-83.

  6. Sánchez-Frenes P, Pérez-Ulloa LE, Sánchez-Bouza MJ, González-Álvarez M, Cuellar-Contreras Y, García-Torres D. Evaluación de la concentración de hemoglobina en donantes regulares de plasma. Rev Cubana Hematol Inmunol Hemoter. 2015; 31 (2): 150-159. Disponible en: http://scielo.sld.cu/scielo.php?script=sci_arttext&pid=S0864-02892015000200006&lng=es.

  7. Regulación No. M 74-14. Buenas prácticas de fabricación para establecimientos de sangre. La Habana: CECMED; 2014. Acceso: 2015/07/18. Disponible en: http://www.cecmed.cu/sites/default/files/adjuntos/Reglamentacion/reg_m_74-14.pdf

  8. Klein HG, Anstee DJ. Exchange transfusion and haemapheresis. In: Klein HG, Anstee DJ. Mollison’s blood transfusion in clinical medicine. 11th ed. Massachusetts: Blackwell Publishing; 2009. pp. 774-809.

  9. Duggan F, O’Sullivan K, Power JP, Healy M, Murphy WG. Serum ferritin in plateletpheresis and whole blood donors. Transfus Apher Sci. 2016; 55 (1): 159-163.

  10. Brecher MA, Hay SN; American Association of Blood Banks. Look it up! (a quick reference in transfusion medicine). United States: AABB Press; 2006.

  11. Bryant BJ, Hopkins JA, Arceo SM, Leitman SF. Evaluation of low red blood cell mean corpuscular volume in an apheresis donor population. Transfusion. 2009; 49 (9): 1971-1976.

  12. Novo-Valdés Y, Sánchez-Frenes P, Benítez-Zayas M, Mediaceja-Vicente O, Noa-López MV, Castellano-González O. Comportamiento evolutivo de variables hematológicas en donantes de plasma. Rev Latinoamer Patol Clin. 2017; 64 (1): 43-49.

  13. Goldman M, Uzicanin S, Scalia V, O’Brien SF. Iron deficiency in Canadian blood donors. Transfusion. 2014; 54 (3 Pt 2) :775-779.




2020     |     www.medigraphic.com