Svarch E, Machín GS, Marcheco TB, Martínez TR, González OA, Menéndez VA

Language: English
References: 6
Page: 1-2
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Cuba has a population of 11 million inhabitants. The percentage of blacks and mixed race is about 30 %. The prevalence of AS trait is 3.04 % in the general population. A prenatal diagnosis has been carried out by the National Center for Medical Genetics since 1986. Until 2012; 4 127 986 pregnant women have been screened: 144 229 had AS or AC trait, and 6 507 were couples at risk. In 5 042 pregnancies, molecular prenatal diagnosis was performed and 992 foetuses were found with sicklecelldisease(SCD) (personal communication). Since 1990, a program for comprehensive SCD care was developed atInstitute of Hematology and Immunology, the leading center for SCD care in Cuba. In the setting of this program, guidelines and a booklet for patients and relatives were written.

REFERENCES

1. Colombo B, Martínez G. Hemoglobinvariants in Cuba. Hemoglobin. 1985; 9: 415-22.

2. Scherle C E, Alvarado JD, Fernández L, Svarch E, González A. Riesgo de ictus isquémico en niños cubanos con anemia drepanocítica. Rev Mexicana Neuroci. 2012; 14 (9):122-6.

3. Svarch E, Nordet I, Machin S, De la Torre E. Partial splenectomy in children with sickle cell disease. Haematologica. 2003; 88 (02):222-3.

4. Svarch E, Nordet I, Gonzalez A. Overhelming septicaemia in a patient with S/β0 thalassaemia. Br J Haematol. 1999 (4); 104:930.

5. Svarch E, Machin S, Nieves RM, Mancia de Reyes AG, Navarrete M, Rodríguez H. Hydroxyurea treatment in children with sickle cell disease in Central América and the Caribbean countries. Pediatr Blood Cancer. 2006(1); 47:111-2.

6. Martinez R, Svarch E, Menendez A, Machado T, Alvarez MA. Capacidad neurocognitiva en niños con drepanocitosis y su relación con el valor de la hemoglobina. Rev Cubana Hematol Inmunol Hemoter. 2011;27(4): 418-28.