medigraphic.com
ISSN 2683-1678 (Print)
Órgano Oficial de la Sociedad
Latinoamericana de lnfectología Pediátrica.
Órgano de la Asociación Mexicana de
Infectología Pediátrica, A.C.
Órgano difusor de la Sociedad Española
de lnfectología

2017, Number 3

Rev Latin Infect Pediatr 2017; 30 (3)

Controversy over the use of triclosan in commonly used antibacterial products

Zúñiga CIR, Caro LJ

Language: Spanish
References: 9
Page: 93-96
PDF size: 172.76 Kb.


ABSTRACT

Triclosan is the most common antiseptic active ingredient used in various types of soap. It is also added to various personal care products and cosmetics, including toothpaste, lotions and shampoos, as well as other products such as clothes, kitchenware, furniture and toys, hand gels, hand wipes with the prevention of bacterial contamination and the growth of bacteria. The use of these products, containing 0.1 to 0.3% of the compound, is absorbed through the mucosa, skin, mouth and gastrointestinal tract. After its absorption, Triclosan is not permanent as free Triclosan and its compounds; are eliminated within 24 hours. The use of triclosan remains controversial because several adverse effects have been reported, including allergies, resistance to antibiotics, endocrine disruptions, acute-chronic toxicity and bioaccumulation; even carcinogenic substances have been identified.


REFERENCES

  1. Gannon M. Triclosan, found in antibacterial soap and other products, causes cancer in mice. The Washington Post. Health & Science. Noviembre 24, 2014.

  2. Dinwiddie MT, Terry PD, Chen J. Recent evidence regarding triclosan and cancer risk. Int J Environ Res Public Health. 2014; 11 (2): 2209-2217.

  3. Scientific Committee on Consumer Safety. Opinion on triclosan. Antimicrobial Resistance. 2010: 1-56.

  4. Kim SA, Moon H, Lee K, Rhee MS. Bactericidal effects of triclosan in soap both in vitro and in vivo. J Antimicrob Chemother. 2015; 70 (12): 3345-3352.

  5. Bhargava HN, Leonard PA. Triclosan: applications and safety. Am J Infect Control. 1996; 24 (3): 209-218.

  6. Adolfsson-Erici M, Pettersson M, Parkkonen J, Sturve J. Triclosan, a commonly used bactericide found in human milk and in the aquatic environment in Sweden. Chemosphere. 2002; 46 (9-10): 1485-1489.

  7. Miller TL, Lorusso DJ, Walsh ML, Deinzer ML. The acute toxicity of penta-, hexa-, and heptachlorohydroxydiphenyl ethers in mice. J Toxicol Environ Health. 1983; 12 (2-3): 245-253.

  8. Saheed A, Agarry O, Abubakar A, Prateek J, Sharma D, Tiwari R. Triclosan resistance in bacteria and antibiotics cross-resistance. Int J Curr Pharm Res. 2012; 4 (4): 88-90.

  9. Food and Drug Adminnistration, HHS. Safety and Effectiveness of Consumer Antiseptics; Topical Antimicrobial Drug Products for Over-the-Counter Human Use. Final rule. Fed Regist. 2016; 81 (172): 61106-61130.




2020     |     www.medigraphic.com