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2002, Number 5

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Gac Med Mex 2002; 138 (5)

Carcinoma renal de células cromófobas. Un estudio clínico patológico de 36 casos.

Alvarado-Cabrero I, Atencio-Chan A, Rodríguez C, Sosa-Romero A

Language: Spanish
References: 15
Page: 421-426
PDF size: 372.40 Kb.


ABSTRACT

Introduction: Chromophobe renal cell carcinoma (CCRC) comprises 5% of neoplasms of renal tubular epithelium. CCRC may have a slightly better prognosis than clear cell carcinoma, but outcome data are limited. Objective: In this study. we analyzed 250 renal cell carcinomas to a) determine frequency of CCRC at our Hospital and b) analyze clinical and pathologic features of CCRCs. Methods: A total of 250 renal carcinomas were analyzed between March 1990 and March 1999. Tumors were classified according to well-established histologic criteria to determine stage of disease; the system proposed by Robson was used Results: Of 250 renal cell carcinomas analyzed, 36 were classified as chromophobe renal cell carcinoma, representing 14% of the group studied. The tumors had an average diameter of 14 cm. Robson staging was possible in all cases, and 10 patients were stage 1) 11 stage II; 10 stage III, and five stage IV. The average follow-up period was 4 years and 18 (53%) patients were alive without disease. Conclusion: The highly favorable pathologic stage (RI-RII, 58%) and the fact that the majority of patients were alive and disease-free suggested a more favorable prognosis for this type of renal cell carcinoma.


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