Rubio-Guerra AF, Arana-Pazos KC, Lozano-Nuevo JJ, Morales-López H, Guerrero-García C, Vargas-Ayala G

Language: Spanish
References: 10
Page: 57-61
PDF size: 110.80 Kb.

ABSTRACT

Objective: To know the cardiometabolic parameters associated with the presence of prehypertension in our environment. Methods: We evaluated 90 patients with prehypertension (31 men and 59 women), in whom blood pressure, weight, height, abdominal circumference, body mass index, as well as blood glucose and lipid profile were recorded, and a group of 90 normotensive subjects (30 men and 60 women), the diagnostic criteria used were the JNC 7 and the 2009 statement of the International Diabetes Federation. The statistical methods used were Odds Ratio and ANOVA. Results: prehypertensive patients presented higher abdominal perimeter, body mass index, as well as higher triglycerides (TG) than normotensive subjects. We found coexistence of metabolic syndrome in 14 normotensive subjects (13.7%), and in 23 prehypertensive patients (37%) the odds ratio for the presence of metabolic syndrome in prehypertensive patients was 3.95 (95% CI 1.8-8.4, p = 0.0004). In addition, prehypertensive patients had a greater coexistence of type 2 Diabetes Mellitus (DM2): the OR for the coexistence of DM2 in prehypertensive patients was 3.17 (95% CI, 1.26-7.98; p = 0.014). Conclusions: Prehypertension increases the risk of presenting metabolic syndrome and DM2; the integral evaluation of these patients will allow to establish prophylactic measures and their management according to the global cardiovascular risk.

REFERENCES

1. The Seven report of the Joint National Committee on Detection, Evaluation,and Treatment of high blood pressure. JNC 7. Complete version. Hypertension 2003;42:1206-1252

2. Rubio-Guerra AF. ¿Se debe tratar la prehipertensión? En: Castro G, Rubio AF. Controversias en síndrome metabólico. México. Editorial Alfil. 2011. Pp. 137-43.

3. Urbina EM, Khoury PR, McCoy C, et al. Cardiac and vascular consequences of prehypertension in youth. J Clin Hypertens (Greenwich). 2011;13:332-342 2008;51:534-539.

4. Guzmán-Guzmán IP, Salgado-Goytia L, Muñoz-Valle JF, Salgado-Bernabé AB, Quiroz- Vargas I, Parra-Rojas I. Prehypertension in a Mexican Population: Influence of Age, Gender, and Body Fat. Clinical and Experimental Hypertension, 2013;35: 67–73

5. Changgui L, Ming-Chia H, Shun-Jen Ch. Metabolic syndrome,diabetes, and hyperuricemia. Curr Opin Rheumatol 2013; 25: 210-16.

6. Rojas R, Aguilar-Salinas CA, Jiménez-Corona A, et al. Metabolic syndrome in Mexican adults: results from the National Health and Nutrition Survey 2006. Salud Publica Mex 2010; 52(Suppl 1): S11-8.

7. Xiao J, Hua T, Shen H, y cols. Associations of metabolic disorder factors with the risk of uncontrolled hypertension: a follow-up cohort in rural China. Sci Rep. 2017;7:743.

8. Alberti KG, Eckel RH, Grundy SM, et al; International Diabetes Federation Task Force on Epidemiology and Prevention; National Heart, Lung, and Blood Institute; American Heart Association; World Heart Federation; International Atherosclerosis Society; International Association for the Study of Obesity. Harmonizing the metabolic syndrome: a joint interim statement of the International Diabetes Federation Task Force on Epidemiology and Prevention; National Heart, Lung, and Blood Institute; American Heart Association; World Heart Federation; International Atherosclerosis Society; and International Association for the Study of Obesity. (2009) Circulation 120:1640-1645.

9. Rubio-Guerra AF. Duran-Salgado MB. Disfunción del tejido adiposo y síndrome metabólico. Sx Cardiometabólico Diabetes 2014;1:31-37

10. Yao W, Sun Y, Wang X, Si Q, Chen H, Wan Z. High prevalence of metabolic syndrome in a middle-aged and elderly population with prehypertension in Tianjin. Clin Exp Hypertens. 2015;37:369-74.