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16 de abril

2016, Number 262

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16 de abril 2016; 55 (262)

Factors associated with cystic neoplasms of the pancreas in patients treated at Hospital 'Arnaldo Milián Castro'. 2004-2014

Hernández-Negrín H, Zurbano FJ, Batista HNE, Rodríguez VRC, Fleites PR, Duménigo RR

Language: Spanish
References: 21
Page: 1-8
PDF size: 403.22 Kb.


ABSTRACT

Introduction: Cystic neoplasms of the pancreas are tumors whose incidence has been increasing in the last decades. There is not a lot of research focused on identifying factors that allow distinguishing between cystic neoplasms of the pancreas and non-neoplastic pancreatic cystic lesions.
Objective: To identify factors associated with cystic neoplasms of the pancreas in patients treated at Hospital "Arnaldo Milián Castro".
Material and methods: An observational and analytical case-control study was performed at Hospital "Arnaldo Milián Castro" in the period 2004-2014. The case group consisted of 15 patients with pancreatic cystic neoplasms and the control group of 30 patients with non-neoplastic pancreatic cystic lesions.
Results: Female gender (93.3%) and white skin color predominated (66.7%); mean age in the case group was 38.9 years. On them, there were significantly higher the presence of smoking habits (OR=2.471; CI=1.068-5.717), diabetes mellitus (OR=2.333; CI=1.094-4.975), weight loss (OR=5.250; CI=2.462-1.1193), anorexia (OR=3.53; CI=1.664-7.499), absence of symptoms (OR=2.909; CI=1.493-5.670) and location of the lesion in the tail of the pancreas (OR=3.692; CI=1.647-8.277 ). Mucinous cystadenoma (53.3%) was more frequently present in the group. The risk factors for the development of pancreatic cystic neoplasms was age between 20-40 (OR = 1.21, CI=1.256-3.995), female gender (OR=1.81; CI=1.658-5.009) and smoking habit (OR=1.95, CI=1.336-9.455).
Conclusions: The factors that were most strongly associated with the presence of pancreatic cystic neoplasms were identified. Its recognition in daily clinical practice could contribute to distinguish between neoplastic and non-neoplastic pancreatic cystic lesions.


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