2017, Number 4
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ABSTRACTThe hemophagocytic syndrome was described for the first time, in 1939, as a febrile condition accompanied by adenomegaly, cytopenias and histiocytic proliferation in the bone marrow; Its incidence is low, it is estimated in one or two cases/million of individuals/year, but most probably, it has been underestimated, on many occasions it is a diagnosis that is not suspected. In this article, it is presented a female patient with an idiopathic reactive hemophagocytic syndrome diagnosed in the Medicine Room D of the Internal Medicine Service of “Arnaldo Milián Castro” Hospital, in which there was no association with immunosuppression, drugs or other infectious process, autoimmune or neoplastic. The aim of this study, besides communicate this case, is to emphasize the importance of the early diagnosis of this disease and the serious alterations that accompany it, responsible for a high mortality rate, as well as a review of the clinical manifestations, pathology and diagnosis and treatment of these patients.
10.Henter JI, Horne A, Arico M, Egeler RM. HLH-2004: Diagnostic and therapeutic guidelines for hemophagocytic lymphohistiocytosis. Pediatr Blood Cancer [Internet]. 2007 Feb [citado 2 Nov 2016];48(2):124-31. Disponible en: https://www.researchgate.net/publication/6851976_HLH-2004_Diagnostic_and_therapeutic_guidelines_for_hemophagocytic_lymphohistiocytosis