2017, Number 1
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Rev Cubana Plant Med 2017; 22 (1)
Importance of pharmacovigilance in herbal medicine
Gruszycki KMR, Tauguinas PAL, Baez CM, Alba DDA, Gruszycki KAE
Language: Spanish
References: 30
Page: 1-10
PDF size: 148.86 Kb.
ABSTRACT
Introduction: Ever since ancient times medicinal herbs have been used to prevent
and treat a variety of diseases. Despite the beneficial traditional role of medicinal
herbs in various communities, their potential for causing adverse reactions and
toxicity should also be borne in mind.
Objective: Analyze the reports of adverse reactions by herbal medicinal products
issued from 2010 to 2016 in the province of Chaco, Argentina.
Methods: A descriptive cross-sectional retrospective study was conducted to
evaluate the reports of adverse reactions received from pharmacies and healthcare
institutions from the province of Chaco, Argentina, at the National System of
Pharmacovigilance of the National Drug, Food and Medical Technology
Administration (ANMAT). The study was based on official forms for the report
adverse events caused by the use of phytotherapeutic drugs, plant products and/or
plant drug preparations.
Results: A total 129 reports were received. Adverse reactions caused by the use of
herbal medicinal products prevailed in the female gender, whereas a large
percentage affected infants and children. Paico (Chenopodium ambrosioides L.) was
the species most commonly reported in this age group and sen (Cassia angustifolia
Vahl.) among adults. Most of the adverse reactions reported were gastrointestinal
disorders. As to intensity and imputability, there was a predominance of mild and
probable reactions, respectively.
Conclusions: Permanent vigilance of herbal medicines is crucial to promote their
safe use, particularly in vulnerable populations.
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