Aceves-Sánchez MJ; González-Salazar F; González-Sánchez D; Bravo-Madrigal J; Flores-Valdez MA

Language: Spanish
References: 19
Page: 123-127
PDF size: 281.51 Kb.

ABSTRACT

Nowadays, tuberculosis (TB) still remains an important public health problem in many countries, including Mexico, where annually about 20,000 new cases and 2,000 deaths from this disease are presented. In our country, the risk of getting TB because of HIV infection is only 2%, compared to 25% in cases of people with diabetes, found both in the southeast and northeast of the Republic. Because of the fact that there are opportunities to improve eff ective screening and diagnosis of tuberculosis in general, and where the methods available today vary even more in patients with diabetes mellitus, in the Centro de Investigación y Asistencia en Tecnología y diseño del Estado de Jalisco, A.C. (CIATEJ). we will seek for and validate compounds derived from the bacteria, looking for the best ones that are recognized by people with diabetes mellitus, and then defi ne the usefulness of these bacterial derived molecules, in the early detection of TB in these patients (use them as biomarkers), ideally before manifesting any complications and evaluate the implementation of preventive therapy in them.

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