Valdés SC, Campo DMC, Hernández GJL, Borrego CG

Language: Spanish
References: 0
Page: 551-556
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ABSTRACT

Introduction: acute myeloid leukemia has a lower incidence in pediatric ages compared to lymphoblastic, which are classified into seven varieties. Although not the most frequent in childhood as it happens in adult stage, it is the one of larger cases of deaths registered, given by the biological characteristics of the disease, associated with a greater number of complications such as bacterial, viral, mycotic infections, as well as bleeding due to thrombocytopenia and coagulopathies. Case report: a 16-year-old boy with a diagnosis of acute myeloid leukemia who after receiving intensive chemotherapy, relapses from his hematologic disease during the maintenance of treatment and dies as a result of intracranial hemorrhage, pseudomona and staphylococcus aureus infection. Conclusion: persistence of neutropenia with exacerbation of infections despite the use of first-line antimicrobial therapy and prolongation of thrombocytopenia linked to loss of integrity of the vascular bed with hemorrhage in lethal sites of the central nervous system that with support of blood products tend to make refractoriness and influence on the mortality rate of these patients.