Díaz-Enriquez E, Mayo-Abad O, Miró-Frutos I, Pérez-Gutiérrez Y, Tsoraeva A

Language: Spanish
References: 0
Page: 54-59
PDF size: 137.08 Kb.

ABSTRACT

In the biopharmaceutical industry, disinfection has become a fundamental part of the activities to control the level of contaminants microorganisms that could compromise the quality of the fi nal product. The objective of this work was to evaluate the effi cacy of the disinfectants Anios Special DJP SF, Aniosurf Premium, Bacteranios SF, Aniospray 29, Aseptanios AD and Surfanios for the cleaning and disinfection of the aseptic area at the Parenterals Products Plant 2 (PPP2) at the National Center for Bioproducts (Mayabeque, Cuba).The effi cacy was checked with challenge tests in surfaces, in practical usage conditions. The number of isolated microorganisms and the microbiota present before and after use was compared statistically. All the disinfectants complied with the established requirements. Therefore, the effi cacy of the disinfectants was demonstrated to perform the cleaning and disinfection of the aseptic areas.