medigraphic.com
SPANISH

Archivos de Neurociencias

Instituto Nacional de Neurología y Neurocirugía
  • Contents
  • View Archive
  • Information
    • General Information        
    • Directory
  • Publish
    • Instructions for authors        
  • medigraphic.com
    • Home
    • Journals index            
    • Register / Login
  • Mi perfil

2016, Number 4

<< Back Next >>

Arch Neurocien 2016; 21 (4)

Chordoma of the lumbar spine mimicking a herniated disc sequestered

Chávez LJA, García CR, Espinoza IF
Full text How to cite this article

Language: Spanish
References: 22
Page: 36-43
PDF size: 358.37 Kb.


Key words:

Classic chordoma, spinal tumors, radiculopathy, disc herniation.

ABSTRACT

Chordomas are rare and slow-growing tumors that arise from remnants of the notochordal cells. The notochord represents embryological origin of the axial skeleton. There may be extrusion of this vestige causing aberrant locations remnants of the notochord and persist along the cranial-spinal axis. The extrusion into the extradural or intradural space allow bone growth without inclusion. We present a rare case of extraosseus and extradural chordoma in a male patient of 65 years with clinical presentation of radiculopathy and an image in the MRI study that mimicked a herniated disc sequestered. The histopathology report was a classic chordoma.


REFERENCES

  1. 1.Kalish G, Brian P, Felix S. Epidural chordoma of the cervical spine with secondary bone involvement. Radiol 2006;1(4):128-33.

  2. 2.Virchow RL. Untersuchungen ueber die Entwicklung des Schaedelgrundes. Berlin: Vg Rimer,1857.

  3. 3.Salisbury JR. The pathology of the human notochord. J Pathol 1993;171:157-65.

  4. 4.Vujovic S, Henderson S, Presneau N. Brachyury, a crucial regulator of notochordal development, is a novel biomarker for chordomas. J Pathol 2006; 209:157-65.

  5. 5.Erdem E, Angtuaco EC, Van Hemert R. Comprehensive review of intracranial chordoma. Radiographics 2003;23:995-1009.

  6. 6.Forsyth PA, Cascino TL, Shaw EG. Intracranial chordomas: a clinicopathological and prognostic study of 51 cases. J Neurosurg 1993; 78:741-7.

  7. 7.Dahlin DC, McCarty CS. Chordoma. Cancer. 1952; 5:1170-78.

  8. 8.Chambers PW, Schwinn CP. Chordoma. A clinicopathologic study of metastasis. Am J Clin Pathol 1979; 72:765-76.

  9. 9.Choi KS, Cohn MJ, Harfe BD. Identification of nucleus pulposus precursor cells and notochordal remnants in the mouse: implications for disk degeneration and chordoma formation. Dev Dyn 2008; 237:3953-58.

  10. 10.Bergh P, Kindblom LG, Gunterberg B. Prognostic factors in chordoma of the sacrum and mobile spine: a study of 39 patients. Cancer 2000; 88:2122-34.

  11. 11.Papagelopoulos P, Mavrogenis A, Galanis E. Chordoma of the spine: clinicopathological features, diagnosis and treatment. Orthopedics.2004;27:1256-86.

  12. 12.Chugh R, Tawbi D, Lucas R, Biermann S. Chordoma: the non-sarcoma primary bone tumor. Oncologist 2007;12:1344-50.

  13. 13.Kaiser TE, Pritchard DJ, Unni KK. Clinicopathologic study of sacrococcygeal chordoma. Cancer 1984; 53:2574-78.

  14. 14.Fourney DR, Gokaslan ZL. Current management of sacral chordoma. Neurosurg Focus 2003; 15:9-12

  15. 15.Tuna H, Aydin V, bozkurt M, Attar A. Chordoma of the lumbar spine: a case report. Neurosurg 2006;16: 169-72.

  16. 16.Mindel ER. Chordoma. J Bone Joint Surg AM 1981; 63:501-5.

  17. 17.Coplan E, Caglar S, Erekul S. Unusually fatal complication of a large sacral cordoma: a case report. Turkish Neurosurgery 2004;14:84-6.

  18. 18.Tomlinson Fh, Scheithauer B, Miller G, Onofrio M. Extraosseus spinal chordoma. J Neurosurg 1991.;75:980-84

  19. 19.Jallo J, Nathan D, Bierbrau K, Farber E. Chordoma: a case report. Surg Neurol 1977; 48:46-8.

  20. 20.Azklund T, Sandstrom M, Shahidi S. Durable Stabilization of three chordoma cases by Bevacizumab and erlotinib. Acta Oncol 2014.Medline.

  21. 21.Causal P, Stachiotti S, Sangalli C, Olmi P. Chordoma. Curr Opin Oncol 2007.19(4):367-70.

  22. 22.Cheryl A, Robinson H. Chordoma, treatment and management. Neurosurg 2016. Medscape




2020     |     www.medigraphic.com

Mi perfil

C?MO CITAR (Vancouver)

Arch Neurocien. 2016;21