Fritz MC, González S, Schilliro L, Moldes S, Del Duca S, De Luján-Calcagno M, Pretti R, Lutfi R, Soutelo J

Language: Spanish
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ABSTRACT

Objective: To define the reference limits of lipid concentrations in uncomplicated gestations.
Material and Method: Observational, retrospective and analytical study carried out in healthy pregnant patients treated in the obstetrics service of the Churruca-Visca Hospital. Inclusion criteria: being pregnant and between 14 and 43 years of age. Exclusion criteria: being in pharmacological treatment that could affect lipid metabolism or have obstetric or neonatal complications.
Results: 163 pregnant women were studied with an average age of 27.2 ± 6.5 years, which was categorized into four groups. In the first trimester non-HDL cholesterol was significantly different among the four categories of BMI (p ‹0.05). In the second quarter, the same results were found for non-HDL and LDL cholesterol (p ‹0.05), while triglyceride concentrations were significantly different according to the five age categories (p ‹0.05). In the third quarter there were no differences in lipid concentrations by age or BMI. Nor were differences obtained by weight gain (less or more than 10 kg).
Conclusion: Lipid and lipoprotein concentrations increased during pregnancy. There was no significant difference between women with low and normal weight versus overweight-obesity. It is necessary to gather more information on reference values of lipids and lipoproteins in order to define the state of dyslipidemia in pregnant women.