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2017, Number 2

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Rev Med MD 2017; 8.9 (2)

Advances in the identification of early biomarkers in Parkinson's disease

Trejo-Ulibarri HM, Solís-S JC
Full text How to cite this article

Language: Spanish
References: 18
Page: 163-169
PDF size: 544.24 Kb.


Key words:

Black substance, dopamine, Lewy bodies, neurodegenerative disease, neuroinflammation, neuromelanin, Parkinson's disease, TNF-alpha.

ABSTRACT

To date in Mexico, there are no epidemiological studies on the prevalence and incidence of Parkinson's disease. There are also no studies of a multicentric nature and with sufficient sample size to develop a demographic and clinical profile of subjects with Parkinson's in the country. However, in our country, a prevalence has been estimated between 40 to 50 cases per 100,000 inhabitants/year. Current evidence suggests clinical heterogeneity in populations of different countries. In this review, we present the etiological, physiopathogenic and clinical aspects and the existing association with some biochemical markers of this multifaceted disease.


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C?MO CITAR (Vancouver)

Rev Med MD. 2017;8.9