2018, Number 1
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Rev Mex Urol 2018; 78 (1)
Advanced collecting duct carcinoma in three patients
Almeida-Magaña R, Aguilar-Davidov B, Priego-Niño A, Castillo-Canto C
Language: Spanish
References: 10
Page: 67-72
PDF size: 329.57 Kb.
ABSTRACT
Background: Collecting duct carcinoma is an extremely rare type
of renal cell carcinoma and accounts for 0.5 to 3% of malignant kidney
cancers. It is an aggressive, rapidly invasive disease that progresses
to early metastasis.
Clinical case: Three cases of advanced-stage collecting duct carcinoma
confirmed through histologic study are reported herein. The
clinical characteristics of the patients were reviewed retrospectively.
All the patients had a history of smoking, were symptomatic at the time
of diagnosis, and presented with advanced-stage disease. The three
patients underwent radical nephrectomy and all died before the end of
two postoperative months: 2 of the deaths were due to postoperative
complications and 1 from early disease progression.
Conclusions: Cytoreductive nephrectomy may be a source of
morbidity and mortality. Larger case series are required to define its
role in the treatment of collecting duct carcinoma.
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