Ayala-Correa A, Saavedra-Mendoza AGM, Akaki-Caballero M

Language: Spanish
References: 11
Page: 1-10
PDF size: 406.03 Kb.

ABSTRACT

Background: Recurrent respiratory papillomatosis (RRP) is a viral disease that causes epithelial exofitic lesions mainly in larynx and trachea with two peaks of presentation, between 2 to 5 years of age and the second to third decades of life. Diagnosis is through flexible laryngoscopy; however, it is not possible the visualization of all the lesions present, so in 2014 the chromoendoscopy was proposed to improve the visualization of lesions with the application of dyes in the mucosa.
Objective: To report the usefulness of chromoendoscopy as a diagnostic and staging method in patients of the Laryngology Clinic in the National Medical Center 20 de Noviembre, Mexico City.
Material and Method: A quasi-experimental study was done from September to November 2015 in over 18 year-old patients with RRP diagnosis, performing in the office a 70^º laryngoscopy with a three-chip camera before and after the application of the indigo carmine dye. The videos obtained were randomized and evaluated by 2 researchers, and the collection and comparison of results by a third researcher. The test of Shapiro-Wilk, Student’s t-test and Kappa coefficient were applied.
Results: A total of 24 videos were captured; in relation to observer 1, at comparing grades obtained with conventional laryngoscopy and chromoendoscopy it was found an increased anatomical grade of Derkay index (t = -2.966, p ‹ 0.05) obtained with chromoendoscopy. Observer 2 also found an increased anatomical grade of Derkay index (t = -2.549, p ‹ 0.05) of chromoendoscopy compared to conventional laryngoscopy.
Conclusions: It is demonstrated the superiority of laryngeal chromoendoscopy for the visualization of lesions and the usefulness of the application of Derkay staging system.

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