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Revista Mexicana de Neurociencia

Academia Mexicana de Neurología, A.C.
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2018, Number 1

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Rev Mex Neuroci 2018; 19 (1)

Neurogenic Pruritus: Response to low-dose levetiracetam. Report of four cases

Marfil A, Garza MAT, Anastacio CJ, Siller RMF, González CJG, Barrera BS
Full text How to cite this article

Language: Spanish
References: 7
Page: 37-43
PDF size: 273.66 Kb.


Key words:

Neurogenic pruritus, treatment, evetiracetam.

ABSTRACT

Introduction: There is no satisfactory treatment for neurogenic pruritus. We present a series of four patients treated successfully with low dose levetiracetam.
Objective: To present the first series of patients with neurogenic pruritus treated successfully with levetiracetam.
Methods: Four case reports
Results: The average interval for clinical response was 3.7 days, and remained while treatment lasted. Only one case had a nonintentional, positive, treatment and retreatment test. There were no side effects attributable to the medication.
Conclusion: At least until this report elaboration, treatment was not suspended, so we cannot speculate about treatment duration.


REFERENCES

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  2. Camille Fleuret and Laurent Misery. Neurogenic Pruritus with Cerebral and/or Medullary Abnormalities. En L. Misery and S. Ständer (eds.), Pruritus, DOI 10.1007/978-1-84882-322-8_23, © Springer-Verlag London Limited 2010.

  3. Binder A, Koroschetz J, Baron R. Disease mechanisms in neuropathic itch. Nat Clin Pract Neurol 2008; 4:329–37.

  4. M Metz, S Ständer. Chronic pruritus – pathogenesis, clinical aspects and treatment. JEADV 2010, 24, 1249–1260

  5. Yalcin Solak, Zeynep Biyik, Huseyin Atalay, Abduzhappar Gaipov, Figen Guney, Suleyman Turk, Adrian Covic, David Goldsmith and Mehmet Kanbay. Pregabalin versus gabapentin in the treatment of neuropathic pruritus in maintenance haemodialysis patients: A prospective, crossover study. Nephrology. 17 (2012) 710–717.

  6. Robert Knobler. Neuropathic Itch as a Presenting Feature of Post-Mastectomy Pain Syndrome. Póster presentado en la reunion anual de la Academia Americana de Neurología. Philadelphia 2014.

  7. Ständer S, Raap U, Weisshaar E, Schmelz M, Mettang T, Handwerker H, Luger TA. Pathogenesis or pruritus. JDDG; 2011 • 9:456–463.




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C?MO CITAR (Vancouver)

Rev Mex Neuroci. 2018;19