Rodríguez MVS, Martín SCC, Díaz CE

Language: Spanish
References: 0
Page: 794-799
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ABSTRACT

Background: ectodermosis pluriorificialis erosive also known as Stevens Johnson syndrome, a minor form of toxic epidermal necrosis, is a serious disease, typically found after taking drugs and related to infections in a lower percentage. Objective: justify the need for the diagnosis and timely treatment of ectodermosis pluriorificialis erosive, due to its appearance as an unexpected serious adverse event when using oral phenytoin. Clinical case: the case referred to a 6-year-old girl who presented this disease in her 10 % body surface. She entered the intensive care unit of the university pediatric hospital "Dr. Eduardo Agramonte Piña", Camagüey province, with symptoms of hemodynamic instability. The ectodermosis pluriorificialis erosive diagnosis is considered as a serious adverse reaction related to the administration of oral phenytoin. The treatment consists on the suspension of the drug, a broad-spectrum intravenous antibiotic treatment, as well as local cure for skin and mucosal lesions. The girl left the hospital with a favorable evolution, without sequels after 25 days of stay. Conclusions: the ectodermosis pluriorificialis erosive was a serious adverse reaction related to the use of phenytoin, hence the importance of timely diagnosis and its treatment.