2013, Number 3
Med Sur 2013; 20 (3)
Sánchez-Valle V, Méndez-Sánchez N
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ABSTRACTThe generation of reactive oxygen species and other free radicals during cellular metabolism is a normal process that is compensated by a complex antioxidant system. However, exposition to environmental, lifestyle, and pathological stressors can lead to the accumulation and excess of free radicals, resulting in oxidative stress. Oxidative stress has been related to aging and chronic diseases that account for a major portion of deaths nowadays. Antioxidants are compounds that hinder the oxidative processes and thereby delay or prevent oxidative stress. This article examines oxidative stress process and the pathways by which it relates to many chronic diseases. We also discuss the role that antioxidants may play in controlling oxidation and review the evidence of their role in disease prevention.