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2018, Number 1

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Med Cutan Iber Lat Am 2018; 46 (1)

Association of type 6 human papillomavirus with hypertrophic lichen sclerosus

Reolid PA, Muñoz AE, Rodríguez JP, Llamas MM, Gordillo C, Daudén E
Full text How to cite this article

Language: Spanish
References: 10
Page: 56-58
PDF size: 362.70 Kb.


Key words:

Lichen sclerosus, human papillomavirus, HPV-6.

ABSTRACT

Verrucous lichen sclerosus is a rare chronic inflammatory disease that sometimes evolves into malignancy. Its association with human papillomavirus remains controversial. We present a case of hypertrophic lichen sclerosus refractory to treatment. The presence of HPV type 6 is demonstrated. The role that this HPV plays in the pathogenesis of the disease and in the clinical form is discussed.


REFERENCES

  1. Gutiérrez-Pascual M, Vicente-Martín FJ, López-Estebaranz JL. Liquen escleroso y carcinoma escamoso. Actas Dermosifiliogr. 2012; 103 (1): 21-28.

  2. Drut RM, Gómez MA, Drut R, Lojo MM. Human papillomavirus is present in some cases of childhood penile lichen sclerosus: an in situ hybridization and SP-PCR study. Pediatr Dermatol. 1998; 15 (2): 85-90.

  3. Perceau G, Derancourt C, Clavel C, Durlach A, Pluot M, Lardennois B et al. Lichen sclerosus is frequently present in penile squamous cell carcinomas but is not always associated with oncogenic human papillomavirus. Br J Dermatol. 2003; 148 (5): 934-938.

  4. Nasca MR, Innocenzi D, Micali G. Association of penile lichen sclerosus and oncogenic human papillomavirus infection. Int J Dermatol. 2006; 45 (6): 681-683.

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  6. Aidé S, Lattario FR, Almeida G, do Val IC, da Costa Carvalho M. Epstein-Barr virus and human papillomavirus infection in vulvar lichen sclerosus. J Low Genit Tract Dis. 2010; 14 (4): 319-322.

  7. D’Hauwers KW, Depuydt CE, Bogers JJ, Noel JC, Delvenne P, Marbaix E et al. Human papillomavirus, lichen sclerosus and penile cancer: a study in Belgium. Vaccine. 2012; 30 (46): 6573-6567.

  8. Smith YR, Haefner HK. Vulvar lichen sclerosus : pathophysiology and treatment. Am J Clin Dermatol. 2004; 5 (2): 105-125.

  9. Weyers W. Hypertrophic lichen sclerosus sine sclerosis: clues to histopathologic diagnosis when presenting as psoriasiform lichenoid dermatitis. J Cutan Pathol. 2015; 42 (2): 118-129.

  10. Henquet CJ. Anogenital malignancies and pre-malignancies. J Eur Acad Dermatol Venereol. 2011; 25 (8): 885-895.




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C?MO CITAR (Vancouver)

Med Cutan Iber Lat Am. 2018;46