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2018, Number 1

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Med Cutan Iber Lat Am 2018; 46 (1)

Merkel cell carcinoma.
Atypical clinical presentation

González RN, Pérez BS, Cancho GG, Blanch RL, Sánchez DA, Izu BR
Full text How to cite this article

Language: Spanish
References: 7
Page: 59-62
PDF size: 353.95 Kb.


Key words:

Merkel cell carcinoma, prognosis, surgery, sentinel lymph node, radiotherapy, chemotherapy.

ABSTRACT

Merkel cell carcinoma is a neuroendocrine cutaneous tumor that appears in the elderly as an erythematous purpuric nodule, which is not clinically very specific, requiring histological study to be diagnosed. In a high percentage of cases, presents loco-regional lymph node involvement, being an aggressive tumor with a high risk of relapse, requiring surgical treatment with adjuvant radiotherapy and/or chemotherapy. An atypical case is presented both by the age of presentation and by its location.


REFERENCES

  1. Ruiz R, Blasco J, Merino J, Linares J, Naranjo R. Carcinoma de células de Merkel. Presentación de seis casos. Actas Dermosifiliogr. 2003; 94 (5): 300-304.

  2. Knopf A, Bas M, Hofauer B, Mansour N, Stark T. Clinicopathological characteristics of head and neck Merkel cell carcinomas. Head Neck. 2017; 39 (1): 92-97.

  3. Hasan S, Liu L, Triplet J, Li Z, Mansur D. The role of postoperative radiation and chemoradiation in merkel cell carcinoma: a systematic review of the literature. Front Oncol. 2013; 3: 276.

  4. Narisawa Y, Koba S, Inoue T, Nagase K. Histogenesis of pure and combined Merkel cell carcinomas: An immunohistochemical study of 14 cases. J Dermatol. 2015; 42 (5): 445-452.

  5. Llombart B, Requena C, Cruz J. Actualización en el carcinoma de células de Merkel: Epidemiología, etiopatogenia, clínica, diagnóstico y estadificación. Actas Dermosifiliogr. 2017; 108 (2): 108-119.

  6. Llombart B, Requena C y Cruz J. Actualización en el carcinoma de células de Merkel: claves de las técnicas de imagen, factores pronóstico, tratamiento y seguimiento. Actas Dermosifiliogr. 2017; 108 (2): 98-107.

  7. Kaufman HL, Russell J, Hamid O, Bhatia S, Terheyden P, D’Angelo SP et al. Avelumab in patients with chemotherapy-refractory metastatic Merkel cell carcinoma: a multicentre, single-group, open-label, phase 2 trial. Lancet Oncol. 2016; 17 (10): 1374-1385.




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C?MO CITAR (Vancouver)

Med Cutan Iber Lat Am. 2018;46