2018, Number 1
Medicentro 2018; 22 (1)
Arce GMA, Díaz SAM, Díaz HM, Hernández MVJ
PDF size: 320.36 Kb.
ABSTRACTIntroduction: platelet concentrates have had multiple uses; their benefits are recently highlighted as basic substrates for obtaining biomaterials that is why this new use results promising as they require, in a reasonable way, the delimitation of their indications, as well as, a better comprehension of the biological processes that lead to regeneration.
Objective: to present the advantages that, based on the evidence, show leukocyte- and platelet-rich fibrin, as an autologous biomaterial used in tissue regeneration.
Methods: the specialized bibliographic search was conducted between October and November 2017 where the most outstanding articles from prestigious databases were selected; 90 % of them were published in the last five years.
Conclusions: tissue regeneration has in leukocyte- and platelet-rich fibrin, a biomaterial that based on the evidence, is showing its relevance of multidisciplinary use. Its advantages go from its autologous nature to its simple and rapid ways to obtain it. The current state of knowledge in this transdisciplinary field suggests the design of new investigations to increase its body of evidence and to establish an adequate regulatory framework for its use.