Travieso ALC, Denis AR, Alonso RC, Dalas GM, Arias PAM, Torres MR, Sanz GDM

Language: Spanish
References: 0
Page: 288-301
PDF size: 442.99 Kb.

ABSTRACT

Rationale: Kidney chronic diseases (CKD) represent the thirteenth cause of death in Cuba. Multisystem complications such as anemia concur in the CKD patient. There are not longitudinal studies about CKD-associated anemia in Cuba. Objective: To document the presence of anemia in the advanced stages of CKD. Study location: Service of Nephrology, “Hermanos Ameijeiras” Hospital (Havana city, Cuba). Study design: Cross-sectional, descriptive. Study serie: Sixty five CKD patients (Males: 52.3%; Ages ≥ 60 years: 43.1%; Evolution time of CKD: 13.2 ± 11.0 years: Subjected to iterative dialysis: 83.1%) assisted at the hospital Service of Nephrology. Material and method: Complete hemograms, along with serum values of iron, transferrin and ferritin, were retrieved from the participating patients. Anemia was established following Hemoglobin cut-off values for each sex: Males: < 140 g.L-1 vs. Females: < 120 g.L-1. Results: Diminished hemoglobin values were present in 67.7% of the study serie. Anemia was independent from CKD stage. Frequency of anemia remained unchanged 6 months after the initial assessment. Conclusions: Anemia found in studied CKD patients occurred within an environment signaled by inflammation and apparent failures during management of the administration schemes of erythropoietin-stimulating agents and iron supplementation. Influence of malnutrition historically associated with CKD upon iron homeostasis should not be overlooked.