Guillén PMF, Fueyo RO, Ruiz BA, Elizondo OÁ,Crabtree RBE, Hoyo UI

Language: Spanish
References: 12
Page: 87-90
PDF size: 176.19 Kb.

ABSTRACT

Introduction: The use of central venous catheters has increased during the last decade. Candida spp. is responsible for 2-11% of catheter-related bloodstream infections in hospitalized patients, with an increase of mortality. The most common risk factors include immunosuppression, broad-spectrum antimicrobial therapy and the use of parenteral nutrition. Candidemia is considered an independent mortality risk factor. Objective: The aim of this study was to identify the epidemiological characteristics and risk factors for catheter-related Candida spp. bloodstream infection. Material and methods: We conducted a retrospective study that evaluated hospitalized patients with diagnosis of catheter-related Candida spp. bloodstream infection. We included demographic, clinical, laboratory and microbiological data from clinical records. We identified the use of parenteral nutrition in the last seven days. Results: We included 16 patients with a mean age of 68 years, 62% were males. 50% had solid or hematological tumors, and 68% had parenteral nutrition in the last seven days. C-reactive protein was higher in patients who died. Candida albicans was the most frequent species isolated. Conclusion: The most common risk factors associated with catheter-related Candida bloodstream infection were malignancy and the use of parenteral nutrition. An elevated C-reactive protein was a marker of poor prognosis.

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