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2018, Number 3

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Rev ADM 2018; 75 (3)

Dental applications of pulpal stem cells of temporary and permanent teeth. Review of in vivo studies

Guadarrama PO, Guadarrama Quiroz LJ, Robles Bermeo NL
Full text How to cite this article

Language: Spanish
References: 63
Page: 127-134
PDF size: 256.68 Kb.


Key words:

Dental pulp stem cell, stem cell therapy, regenerative dentistry, clinical trial.

ABSTRACT

Stem cell therapy had attracted the medical attention as an alternative to organ transplantation, considering the characteristics these cells have in vivo. In recent years, dentistry has aroused great level of interest in the potential therapeutic of stem cells derived from dental pulp tissue. The main characteristic of dental pulp stem cells is the high capacity of proliferation, multidifferentiation, self-renewal and the ability to differentiate into other cell types such as odontoblasts, osteoblasts, adipocytes, chondrocytes and neural cells. In regard to multipotential cells there is a high probability about dental tissue regeneration as well as the material substitution, which are currently used in dentistry by biological materials. Therefore scientific studies and experiments in vivo have proved the usefulness and feasibility of pulp stem cells for treatment of buccal lesions, as well as therapeutic potential and tissue regeneration. In this review are included in vivo studies about the dental applications of stem cells from primary and permanent teeth. The potential tissue regeneration, benefits and clinical applications are shown, aimed to provide punctual and complete information to readers about the safety and therapeutic scope with dental pulp stem cells, focused on regeneration, replacement of tissues and organs of the oral cavity.


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Rev ADM. 2018;75