Cruz HJ, Castelo Elías-Calles L, Valdés RH, Domínguez AE, Yanes QM, Hernández GP

Language: Spanish
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Page: 1-15
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ABSTRACT

Introduction: dyslipidemia is a frequent vascular risk factor in type 2 diabetes.
Objective: to identify the relation between lipid alterations and vascular risk in type 2 diabetes.
Methods: cross-sectional and correlational study of 111 people with type 2 diabetes and dyslipidemia (41 of them with primary and 70 with secondary) attended at the Diabetics Care Center of the National Institute of Endocrinology during 2014-2015. The variables analyzed were: age, sex, smoking habit, body mass index, waist circumference, waist-hip and waist-height indexes, systolic and pulse blood pressure, total cholesterol, low density lipoproteins and high density lipoproteins, triglycerides, apoproteins A and B, glycosylated hemoglobin, carotid intima-media complex; and cardiovascular risk by WHO and Gaziano tables. To compare qualitative variables (percentage), Fisher's test was used, and for quantitative (± DE), Mann-Whitney U. For all analyzes, a p ‹ 0.05 was assumed.
Results: the decrease of high density-cholesterol´s lipoproteins was the alteration of lipid fraction that was more related to the alteration of clinical and biochemical variables, for both dyslipidemias. Primary dyslipidemia was associated with a higher cardiovascular risk according to WHO tables (p= 0.015).
Conclusions: primary dyslipidemia and the decrease of high density-cholesterol´s lipoproteins were associated with a higher vascular risk.