Vasconcelos ELC, Larrondo MHM, Mora DI

Language: Spanish
References: 0
Page: 185-196
PDF size: 153.57 Kb.

ABSTRACT

Introduction: There is an imbalance between procoagulant activities and anticoagulants in critical patients, so coagulation disorders or coagulopathies are a frequent complication associated with high morbidity and mortality.
Objectives: To identify risk factors associated with acquired coagulopathies in hospitalized patients and to analyze the relationship between coagulopathy and mortality.
Methods: A prospective longitudinal study was carried out. Complementary and clinical histories of 29 patients were reviewed. These patients had been admitted to the intensive care unit at Hermanos Ameijeiras hospital from April to June 2011. Risk factors associated with coagulopathies were identified. Mortality relationship was analyzed.
Results: The presence of coagulopathies on admission was identified in 58.62 %, 44.82 % in 48-72 h and 51.73 % in last assessment. Coagulopathy was predominant due to deficiency of vitamin K dependent factors. The use of blood components and the administration of aminoglycosides were statistically significant in the unit. Twenty one (21) patients died and thirteen (13) coagulopathy was detected, (44.8 %).
Conclusions: It was detected that it is twice as likely that the person receiving hemocomponents will develop some type of coagulopathy and five times more likely if they are administered aminoglycosides. No significant relationship was found between the presence of coagulopathy and mortality, nor significant relationship between the presence of bleeding and mortality.