medigraphic.com
SPANISH

Cirujano General

ISSN 2594-1518 (Electronic)
ISSN 1405-0099 (Print)
  • Contents
  • View Archive
  • Information
    • General Information        
    • Directory
  • Publish
    • Instructions for authors        
    • Send manuscript
  • medigraphic.com
    • Home
    • Journals index            
    • Register / Login
  • Mi perfil

2018, Number 1

<< Back Next >>

Cir Gen 2018; 40 (1)

Bee honey added to the surgical management of intra-abdominal sepsis. Report of two cases

Mejía-Rendón G, Mejía-Pérez CI
Full text How to cite this article

Language: Spanish
References: 24
Page: 31-37
PDF size: 381.64 Kb.


Key words:

Bee honey, intra-abdominal sepsis, peritoneal lavage.

ABSTRACT

Among the attributes of bee honey, its antimicrobial properties stand out. In foreign countries, there are already therapeutic kinds of honey, especially for the treatment of wounds. There is ongoing research with experimental studies that have used honey even for the prevention of intra-abdominal adhesions due to peritonitis. Surgical treatment of intra-abdominal sepsis (IAS) may include peritoneal lavage and other strategies according to its severity. We report two severe cases of this condition with an unfavorable prognosis, in which intra-abdominal honey was used as an adjunct, expecting an antimicrobial activity. Clinical progress in both patients was favorable. The use of honey is supported by literature and previous experience, and by attempts to prevent persistent peritonitis. From what is known about honey, benefits in IAS may be expected, since it use look promising. Although recognizing its limitations, honey could be an adjuvant to therapeutic interventions or surgical approaches when necessary.


REFERENCES

  1. Eteraf-Oskouei T, Najafi M. Traditional and modern uses of natural honey in human diseases: a review. Iran J Basic Med Sci. 2013; 16: 731-742.

  2. Olaitan PB, Adeleke OE, Ola IO. Honey: a reservoir for microorganisms and an inhibitory agent for microbes. Afr Health Sci. 2007; 7: 159-165.

  3. Kwakman PH, Te Velde AA, De Boer L, Vandenbroucke-Grauls CM, Zaat SA. Two major medicinal honeys have different mechanisms of bactericidal activity. PLoS One. 2011; 6: e17709. PubMed Central. PMCID: PMC 3048876

  4. Carter DA, Blair SE, Cokcetin NN, Bouzo D, Brooks P, Schothauer R, et al. Therapeutic manuka honey: no longer so alternative. Front Microbiol. 2016; 7: 569. PubMed Central. PMCID: PMC 4837971

  5. Majtan J. Methylglyoxal —A potential risk factor of manuka honey in healing of diabetic ulcers. Evid based Complement Alternat Med. 2011; 2011: 295494: PubMed Central. PMCID: PMC 3135160

  6. Zaid SSM, Othman S, Kassim NM. Potential protective effect of Tualang honey on BPA-induced ovarian toxicity in prepubertal rat. BMC Complement Altern Med. 2014; 14. article 509: 12. PubMed Central. PMCID: PMC 4301897

  7. Aznan MI, Khan OH, Unar AO, Tuan Sharif SE, Khan AH, Syed Abd Aziz SH, et al. Effect of Tualang honey on the anastomotic wound healing in large bowel anastomosis in rats —A randomized controlled trial. BMC Complement Altern Med. 2015; 16: 28. PubMed Central. PMCID: PMC 4724403

  8. Emre A, Akin M, Isikgonul I, Yuksel O, Anadol AZ, Cifter C. Comparison of intraperitoneal honey and sodium hyaluronate-carboxymethylcellulose (Seprafilm) for the prevention of postoperative intra-abdominal adhesions. Clinics (Sao Paulo). 2009; 64: 363-368.

  9. Burnett WE, Brown GR Jr, Rosemond GP, Caswell HT, Buchor RB, Tyson RR. The treatment of peritonitis using peritoneal lavage. Ann Surg. 1957; 145: 675-682.

  10. Qadan M, Dajani D, Dickinson A, Polk HC Jr. Meta-analysis of the effect of peritoneal lavage on survival in experimental peritonitis. Br J Surg. 2010; 97: 151-159.

  11. Hesami MA, Alipour H, Nikoupour DH, Alipour B, Bazargan HS, Ahmadi A. Irrigation of abdomen with imipenem solution decreases surgical site infections in patients with perforated appendicitis: a randomized clinical trial. Iran Red Crescent Med J. 2014; 16: e12732. PubMed Central. PMCID: PMC 4028767

  12. Parcells JP, Mileski JP, Gnagy FT, Haragan AF, Mileski WJ. Using antimicrobial solution for irrigation in appendicitis to lower surgical site infection rates. Am J Surg. 2009; 198: 875-880.

  13. Montravers P, Dufour G, Guglielminotti J, Desmard M, Muller C, Houissa H, et al. Dynamic changes of microbial flora and therapeutic consequences in persistent peritonitis. Crit Care. 2015; 19: 70. PubMed Central. PMCID: PMC 4354758

  14. Billing A, Frolich D, Scildberg FW. Prediction of outcome using the Mannheim peritonitis index in 2003 patients. Br J Surg. 1994; 81: 209-213.

  15. Gonzalez- Aguilera JC. Pronóstico de la peritonitis generalizada según el índice de Mannheim. Cir Gen. 2002; 70: 179-182.

  16. Jansen SA, Kleerekooper I, Hofman ZL, Kappen IF, Stary-Weinzinger A, Van Der Heyden MA. Grayanotoxin poisoning: “Mad honey disease” and beyond. Cardiovasc Toxicol. 2012; 12: 208-215.

  17. Al-Waili N, Salom K, Al-Ghamdi A, Ansari MJ. Antibiotic, pesticide, and microbial contaminants of honey: human health hazards. Sci World J. 2012; 2012: 930849. PubMed Central. PMCID: PMC 3477659

  18. Schwartz KL, Austin JW, Science M. Constipation and poor feeding in an infant with botulism. CMAJ. 2012; 184: 1919-1922.

  19. Abdulla CO, Ayubi A, Zulfiquer F, Santhanam G, Ahmed MAS, Deeb J. Infant botulism following honey ingestion. BMJ Case Rep. 2012; 2012. PubMed central. PMCID: PMC 3448763

  20. Loganathan A. Intraabdominal sepsis. Surgery. 2015; 33: 553-558.

  21. Vallejo Soto M. Sepsis abdominal. Rev Gastroenterol Mex. 2007; 72: 110-113.

  22. Mejía-Rendón G, Mejia-Pérez SI. Bolsa de Bogotá resistente en abdomen abierto. Cir Gen. 2012; 34: 54-57.

  23. Petrowsky H, Demartines N, Rousson V and Clavien PA. Evidence-based value of prophylactic drainage in gastrointestinal surgery. a systematic review and meta-analyses. Ann Surg. 2004; 240: 1074-1085.

  24. Grade M, Quintel M, Ghadimi BM. Standard perioperative management in gastrointestinal surgery. Langenbecks Arch Surg. 2011; 396: 591-606.




2020     |     www.medigraphic.com

Mi perfil

C?MO CITAR (Vancouver)

Cir Gen. 2018;40