Franco AO, Coca ÁG, Domínguez DF, Andrés AD, Andino AD

Language: Spanish
References: 0
Page: 1-11
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ABSTRACT

Introduction: neonatal hypoxic-ischemic encephalopathy intensively expresses its consequences during childhood and infancy. Despite the important therapeutical advances, it is a cause of mortality and neurological disability and this situation is not expected to change in a significant way in the coming years.
Objective: to characterize the neonates with hypoxic encephalopathy according to clinical and biochemical variables and to neurological sequelae.
Methods: a longitudinal and descriptive research was conducted in 46 neonates cared at "10 de Octubre" university maternal hospital from 2012 to 2015. The study variables were gestational age and birth weight, Apgar at the 5th minute of life, gasometry values, neurological assessment and neurodevelopmental disorders. The chi-square test and the Duncan´s multiple range test were used.
Results: over 95 % of the sample were term neonates. Seventy two percent required intensive resuscitation for the first ten minutes of life. In the first hour, the Ph of patients was lower than 7.20 and severe acidemia was observed in more than 50 %. Moderate hypoxic encephalopathy was over 70 %. Ninety one percent managed to survive, but all of them had some kind of neurodevelopmental disorder.
Conclusions: among the neonates with hypoxic encephalopathy, the term newborns predominate. A significant number of them require resuscitation on the 10th minute of life and show moderate to severe academia. Moderate hypoxic encephalopathy progressively prevails. The survivors have some kind of neurodevelopmental disorder, either transient or permanent.