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Órgano Oficial del Instituto Nacional de Psiquiatría Ramón de la Fuente Muñiz

2018, Number 3

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Salud Mental 2018; 41 (3)

Autism, the current pathological trend in psychiatry

Nicolini H

Language: English
References: 18
Page: 105-107
PDF size: 218.93 Kb.


Text Extraction

In the past decade, autistic spectrum disorders (ASD) have received great attention from society, as well as funding for biomedical research. This has been reflected in the significant increase in scientific publications on the subject. It should be noted that in 2000 there were only approximately 500 publications in PubMed whereas there are currently over 40,000. Accordingly, autism has become one of the most representative conditions in neuroscientific development in current psychiatry. In recent years, novel results have been obtained in the identification of autism genes through various methodologies such as cytogenetic studies, allelic association, genome and exome screening, and epigenetics. The genetic architecture of autism is complex since hundreds of genes interact in its etiology, producing different effects on the phenotype. Despite progress in both the clinical aspect and research on animal models, it is not easy to establish a diagnosis in everyday clinical practice, except for certain causes of syndromic autism secondary to fragile-X syndrome or Rett syndrome, among other variants which it is already possible to diagnose (Muhle, Reed, Stratigos, & Veenstra-VanderWeele, 2018).


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