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2018, Number 1

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RCU 2018; 7 (1)

Behavior of renal function in the surgery of renal tumors

González LT, Sánchez TR, Morera PM

Language: Spanish
References: 24
Page: 20-28
PDF size: 737.26 Kb.


ABSTRACT

Introduction: Surgery is the treatment of choice in located renal cancer and radical nephrectomy is the most frequent surgery, entailing loss of renal function (chronic kidney disease). The increase of diagnosis at initial stages has encouraged treatment by nephron-sparing surgery. Objective: To assess renal function in patients who underwent laparoscopic surgery of parenchymal renal tumors. Methods: A retrospective study was carried out at the National Center of Minimally Invasive Surgery between 2010 and 2016 in patients undergoing laparoscopic radical nephrectomy (LRN) or laparoscopic nephron-sparing surgery (LNSS). We considered pre and post-operative estimated glomerular filtration rate (e-GFR) the main variable. Results: The estimated preoperative GFR was significantly than in the postoperative period. In the LRN group, more patients developed CKD, but it was not significant (p= 0.0470) with respect to LNSS. Conclusions: Postoperative GFR was significantly lower than preoperative GFR in laparoscopic surgery for renal tumor, regardless of the type of surgery. LNSS had better filtrado glomerular, although the difference was not significant with respect to LRN.


REFERENCES

  1. Galsky MD. Metastatic renal cancer: better never than late. EurUrol. 2014 [citado 20 May 2017];65(6):1093-4. doi: 10.1016/j.eururo.2013.08.004 Disponible en: https://www.ghrnet.org

  2. Siegel RL, Miller KD, Jemal A. Cancer statistics, 2015. CA Cancer J Clin. 2015 [citado 20 May 2017];65(1):5-29. doi: 10.3322/caac.21387. Disponible en: https://www.ncbi.nlm.nih.gov/pubmed

  3. Kang TW, Hwang EC. Renal function after nephron-sparing surgery. J Nephrology Research. 2015 [citado 20 May 2017];1(3):97-8. Disponible en: https://www.ghrnet.org

  4. García AG, León TG. Simple enucleation for renal tumors: indications, techniques, and results. CurrUrol Rep. 2016 [citado 20 May 2017];17(1):7. doi: 10.1007/s11934-015-0560-4. Disponible en: https://www.ncbi.nlm.nih.gov/pubmed

  5. Nisen H, Heimonen P, Kenttä L, Visapää H, Nisen J, Taari K. Renal tumour anatomical characteristics and functional outcome after partial nephrectomy. Scand J Urol. 2015 [citado 21 May 2017];49(3):193-9. doi: 10.3109/21681805.2014.978819. Disponible en: https://www.ncbi.nlm.nih.gov/pubmed

  6. Albiges L, Choueiri T, Escudier B, Galsky M, George D, Hofmann F, et al. A systematic review of sequencing and combinations of systemic therapy in metastatic renal cancer. Eur Urol. 2015;67(1):111-3. doi: 10.1016/j.eururo.2014.04.006. Disponible en: https://www.ncbi.nlm.nih.gov/pubmed

  7. Demirjian S, Lane BR, Derweesh IH, Takagi T, Fergany A, Campbell SC. Chronic kidney disease due to surgical removal of nephrons: relative rates of progression and survival. J Urol. 2014 [citado 31 May 2017];92(4):1057-63. doi: 10.1016/j.juro.2014.04.016. Disponible en: https://www.ncbi.nlm.nih.gov/pubmed

  8. Patel SG, Penson DF, Pabla B, Clark PE, Cookson MS, Chang SS, et al. National trends in the use of partial nephrectomy: a rising tide that has not lifted all boats. J Urol. 2012 [citado 11 Jul 2017];187(3):816-21. doi: 10.1016/j.juro.2011.10.173. Disponible en: https://www.ncbi.nlm.nih.gov/pubmed

  9. Ljungberg B, Bensalah K, Canfield S, Dabestani S, Hofmann F, Hora M, et al. EAU guidelines on renal cell carcinoma: 2014 update. Eur Urol. 2015;67(5):913-24. doi: 10.1016/j.eururo.2015.01.005. Disponible en: https://www.ncbi.nlm.nih.gov/pubmed

  10. Chaple EB. La Salud Pública en Cuba: Años 2005-2014. International Journal of Cuban Studies. 2016;8(2):217-62. doi: 10.13169/intejcubastud.8.2.0217. Disponible en: http://www.jstor.org/stable/10.13169

  11. Akbari A, Clase CM, Acott P, Battistella M, Bello A, Feltmate P, et al. Canadian Society of Nephrology commentary on the KDIGO clinical practice guideline for CKD evaluation and management. Am J Kidney Dis. 2015 [citado 11 Jun 2017];65(2):177-205. doi: 10.1053/j.ajkd.2014.10.013. Disponible en: https://www.ncbi.nlm.nih.gov

  12. Eppenga WL, Kramers C, Derijks HJ, Wensing M, Wetzels JF, De Smet PA. Individualizing pharmacotherapy in patients with renal impairment: the validity of the Modification of diet in renal disease formula in specific patient populations with a glomerular filtration rate below 60ml/min. A systematic review. PLoS One. 2015 [citado 31 Jul 2017];10(3):e0116403. Disponible en: https://www.ncbi.nlm.nih.gov/pubmed

  13. Anuario Estadístico de Salud 2015. Dirección de Registros Médicos y estadísticos de Salud. La Habana: Ministerio de Salud Pública; 2016 [citado 31 Jul 2017]. Disponible en: http://files.sld.cu/dne/files/2016/04/Anuario_2 015_electronico-1.pdf

  14. Lane BR, Campbell SC, Demirjian S, Fergany AF. Surgically induced chronic kidney disease may be associated with a lower risk of progression and mortality than medical chronic kidney disease. J Urol. 2013 [citado 31 Jul 2017];189(5):1649-55. doi: 10.1016/j.juro.2012.11.121. Disponible en: https://www.ncbi.nlm.nih.gov/pubmed

  15. Shetty AV, Matrana MR, Atkinson BJ, Flaherty AL, Jonasch E, Tannir NM. Outcomes of patients with metastatic renal cell carcinoma and end-stage renal disease receiving dialysis and targeted therapies: a single institution experience. Clin Genitourin Cancer. 2014;12(5):348-53. doi: 10.1016/j.clgc. 2014.01.004. Disponible en: https://www.ncbi.nlm.nih.gov/pubmed

  16. Scosyrev E, Messing EM, Sylvester R, Campbell S, Van Poppel H. Renal function after nephron-sparing surgery versus radical nephrectomy: results from EORTC randomized trial 30904. Eur Urol. 2014 [citado 31 May 2017];65(2):372-7. doi: 10.1016/j.eururo.2013.06.044. Disponible en: https://www.ncbi.nlm.nih.gov/pubmed

  17. Takagi T, Kondo T, Iizuka J, Kobayashi H, Hashimoto Y, Nakazawa H, et al. Postoperative renal function after partial nephrectomy for renal cell carcinoma in patients with pre-xisting chronic kidney disease: A comparison with radical nephrectomy. Int J Urol. 2011[citado 31 Jul 2017];18(6):472-6. doi: 10.1111/j.1442- 2042.2011.02765.x. Disponible en: https://www.ncbi.nlm.nih.gov/pubmed

  18. Kim SP, Thompson RH, Boorjian SA, Weight CJ, Han LC, Murad MH, et al. Comparative effectiveness for survival and renal function of partial and radical nephrectomy for localized renal tumors: a systematic review and metaanalysis. J Urol. 2012 [citado 31 May 2017];S0022-5347(12):05254-8. doi: 10.1016/j.juro.2012.10.026. https://www.ncbi.nlm.nih.gov/pubmed

  19. Pierorazio PM, Hyams ES, Lin BM, Mullins JK, Allaf ME. Laparoscopic radical nephrectomy for large renal masses: critical assessment of perioperative and oncologic outcomes of stage T2a and T2b tumors. Urology. 2012 [citado 22 May 2017];79(3):570-5. doi: 10.1016/j.urology.2011.10.065. Disponible en: https://www.ncbi.nlm.nih.gov/pubmed

  20. Gu C, Zhang H, Dai B, Zhu Y, Shi G, Shen Y, et al. Comparison of the renal function after partial nephrectomy and radical nephrectomy for T1a renal cell carcinoma. Zhonghua Zhong Liu Za Zhi. 2015 [citado 23 May 2017];37(6):441-4. Disponible en: https://www.ncbi.nlm.nih.gov/pubmed

  21. Sosnowski R, Benke M, Demkow T, Ligaj M, Michalski W. Renal function after nephronsparing surgery for renal tumors. Cent European J Urol. 2012 [citado 23 May 2017];65(1):14-6. doi: 10.5173/ceju.2012.01. Disponible en: https://www.ncbi.nlm.nih.gov/pubmed

  22. Pansadoro A, Cochetti G, D'amico F, Barillaro F, Del Zingaro M, Mearini E. Retroperitoneal laparoscopic renal tumourenucleation with local hypotension on demand. World J Urol. 2015 [citado 31 May 2017];33(3):427-32. doi: 10.1007/s00345-014-1325-2. Disponible en: https://www.ncbi.nlm.nih.gov/pubmed

  23. Tomaszewski JJ, Uzzo RG, Kutikov A, Hrebinko K, Mehrazin R, Corcoran A, et al. Assessing the burden of complications after surgery for clinically localized kidney cancer by age and comorbidity status. Urology. 2014 [citado 31 Jul 2017];83(4):843-50. doi: 10.1016/j.urology.2013.12.048. Disponible en: https://www.ncbi.nlm.nih.gov/pubmed

  24. González T, Morera M. Renal Cancer in the Elderly. Curr Urol Rep. 2016 [citado 11 Ago 2017];17(1):6. Disponible en: https://link.springer.com




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