García MAJ, Santos ML, Ciria MA

Language: Spanish
References: 0
Page: 406-419
PDF size: 81.01 Kb.

ABSTRACT

Introduction: for the Cuban System of Pharmacovigilance, the detection occasionally adverse, rare or very rare, and even non-described is important. This is the starting point to generate hypotheses of casual relations between drug administration and the emergency of a determinate adverse effect.
Objective: to describe the type B adverse reactions in Cuba that have been notified to the pharmacovigilance system and the immunologic bases for their interpretation.
Material and methods: it was carried out a documental research and a content analysis of the identified national and international publications dealing with the theme.
Results: the theoretical and methodological elements for dealing with drug consumption security, pharmacovigilance and drug adverse reactions are given, and also their immunologic interpretation and type B low-frequency profile.
Conclusions: the type B adverse reaction´s profile in Cuba is high; therefore their study, taking into account their immunologic interpretation is a valuable information for characterizing drugs security and for taking decisions in public health care.