Morales YRA, Sierra PL, Triana DA

Language: Spanish
References: 0
Page: 68-77
PDF size: 548.57 Kb.

ABSTRACT

Cancer is a major public health problem in the world. Chemotherapy is indicated in several phases of the antineoplastic treatment, either as neoadjuvant, adjuvant or palliative therapy. One of the most worrisome side effects generated by chemotherapy is cardiotoxicity, and one of the main symptoms is heart failure, secondary to damage to the myocardium due to the direct and indirect toxicity of antineoplastic therapies. The objective of this article is to review the state of the art of the chemotherapy-induced cardiotoxicity, as well as to synthesize the different cardiotoxic effects, cardiotoxic mechanisms and methods that have been developed for its diagnosis and prevention.