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2018, Number 1

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Cir Cir 2018; 86 (1)

Parkinsonism as presenting symptom of primary hyperparathyroidism: Improvement after surgery

Luján-Martínez D, Sánchez-Cifuentes Á, Peña-Ros E, Albarracín-Marín-Blázquez A, Candel-Arenas MF
Full text How to cite this article

Language: Spanish
References: 5
Page: 105-107
PDF size: 193.58 Kb.


Key words:

Parkinsonism, Primary hyperparathyroidism, Hypercalcemia.

ABSTRACT

Introduction: Hypercalcemia can cause different neurological disorders, depending on the calcium level. We report an exceptional case of primary hyperparathyroidism presenting as neurological alteration and it has favourable outcome after parathyroidectomy. Case report: A 74-year-old woman presented with progressive cognitive deterioration and impaired motor function. The complementary tests showed hypercalcemia due to a parathyroid adenoma. Parathyroidectomy was performed with symptomatic improvement. Conclusion: Cognitive impairment of the elderly due to a parathyroid adenoma is underdiagnosed, behavioral changes and alterations of motor functions are attributed to age, dementia and frailty, representing a diagnostic challenge.


REFERENCES

  1. Lourida I, Thompson-Coon J, Dickens CM, Soni M, Kuźma E, Kos K, et al. Parathyroid hormone, cognitive function and dementia: a systematic review. PLoS One. 2015;10 e0127574.

  2. Bandeira L, Bilezikian J. Primary hyperparathyroidism. F1000 Research. 2016;5:F1000 Faculty Rev-1.

  3. Hirooka Y, Yuasa K, Hibi K, Ishikawa A, Sobue G, Naruse T, et al. Hyperparathyroidism associated with parkinsonism. Intern Med. 1992;31:904-7.

  4. Kovacs CS, Howse DC, Yendt ER. Reversible parkinsonism induced by hypercalcemia and primary hyperparathyroidism. Arch Intern Med. 1993;153:1134-6.

  5. De Rosa A, Rinaldi C, Tucci T, Pappata S, Rossi F, Morra VB, et al. Co-existence of primary hyperparathyroidism and Parkinson’s disease in three patients: an incidental finding? Parkinsonism Relat Disord. 2011;17:771-3.




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Cir Cir. 2018;86