Espinosa SA, Pérez GH

Language: Spanish
References: 13
Page: 68-75
PDF size: 197.54 Kb.

ABSTRACT

Salt (NaCL) is the most abundant component of extracellular fluid and regulates the constancy of serum osmolality and cellular tonicity. This constancy is lost in patients with end stage renal disease. Dialysis, in general, and hemodialysis, in particular, correct or improved these alterations in patients with chronic renal failure. Modifications in the sodium concentration in the dialysis solution [NaD] add or remove salt from the body during the dialysis procedure and change the serum sodium concentration [NaS]. In the initial hemodialysis programs (1970), the use of this methodology allowed the change in the serum sodium concentration, better blood pressure control and improvement of the hemodynamic imbalances. In the last years, with the data obtained from the DOPPS study, the individualization of the sodium dialysate with the serum sodium concentration during the hemodialysis session improved the clinical response to ultrafiltration, decreased the trans-dialysis symptoms and complications, the inter-dialysis thirst and the weight gain. All these factors lead to a better blood pressure control and a better adaptive response of the left ventricle, reduction in the number of hospitalizations and other co-morbidities.

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