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2018, Number 2

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Mediciego 2018; 24 (2)

Relationship between plasma testosterone levels and some clinical and imaging parameters in patients with prostate cancer

Parés OYM, García MY, Marrero HSA, Casa ME, Toledo FBR, Trujillo TT
Full text How to cite this article

Language: Spanish
References: 0
Page: 24-33
PDF size: 85.35 Kb.


Key words:

prostatic neoplasms/diagnosis, testosterone/blood, L-lactate dehydrogenase/blood, alkaline phosphatase/blood, tumor biomarkers/blood, diagnostic imaging/parameters, signs and symptoms/parameters.

ABSTRACT

Introduction: prostate cancer is the solid tumor that appears most frequently in men older than 50 years.
Objective: to describe the relationship between plasma testosterone levels and some clinical and imaging parameters in patients with prostate cancer treated at the General Provincial Teaching Hospital in Ciego de Ávila.
Method: a cross-sectional descriptive study was carried out in the period from January 2012 to December 2015. The population studied was constituted by 117 patients with histological confirmation of the disease.
Results: groups of 76-85 years (36,75 %) and 66-75 years (34,19%) predominated. All of them presented high levels of prostate-specific antigen, and of these 94,87 % with high risk. The majority (95,73%) did not presented testosterone levels in castration figures. The main imaging lesions were located in the prostate (77,78 %). The tumor markers were elevated: lactate dehydrogenase (65,81%) and alkaline phosphatase (64,10 %). Only 5,15 % of those who had affected two lobes of the prostate, had levels in castration values. 94, 51 % of the patients with testosterone levels above the castration values only presented lesions in the prostate without metastasis according to the imaging studies.
Conclusions: the results of the digital physical examination of the prostate and the imaging studies had no relation with the plasma testosterone values after the hormonal treatment.





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Mediciego. 2018;24