medigraphic.com
SPANISH

Revista de Investigación Clínica

Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán
  • Contents
  • View Archive
  • Information
    • General Information        
    • Directory
  • Publish
    • Instructions for authors        
  • medigraphic.com
    • Home
    • Journals index            
    • Register / Login
  • Mi perfil

2018, Number 4

<< Back Next >>

Rev Invest Clin 2018; 70 (4)

Primary Tumors of the Central Nervous System. Clinical Experience at a Third Level Center

Hernández-Hernández A, Reyes-Moreno I, Gutiérrez-Aceves A, Guerrero-Juárez V, Santos-Zambrano J, López-Martínez M, Castro-Martínez E, Cacho-Díaz B, Avendaño Méndez-Padilla J, González-Aguilar A
Full text How to cite this article

Language: English
References: 22
Page: 177-183
PDF size: 134.42 Kb.


Key words:

Central Nervous System, Primary brain tumors, Neuroepithelial tumors, Incidence, Men, Metastatic tumors (Mets).

ABSTRACT

Background: Central nervous system (CNS) tumors are a group of neoplasms that originate from various cells in the CNS. The increasing incidence and prevalence of this type of tumor in developing countries are striking; however, there are few current studies in Latin America including Mexico estimating the impact of these pathological entities on the general population. Objective: The objective of the study was to study the characteristics of primary CNS tumors over a period of 52 years. Methods: A review of records from patients with a histopathological diagnosis of CNS neoplasm over a period of 52 years was conducted at a tertiary-care academic medical center. Patients were grouped by sex, age, and the tumor’s anatomical location. Results: A sample of 9615 patients with tumor lesions was obtained; 51% were female, 49% were male, and their mean age was 42 years. The tumors with the highest prevalence were neuroepithelial tumors (38.6%), followed by meningeal tumors (22.8%). Neuroepithelial tumors accounted for 64% in the group of patients under 40 years of age and 56% among those above 40 years of age. The most frequently involved location was supratentorial, in 78.9% of cases. Conclusions: Although retrospective in nature and based on a small sample, this study reports the epidemiology and characteristics of primary brain tumors in the Mexican population.


REFERENCES

  1. Kasper DL, Fauci AS, Hauser SL, Longo DL, Jameson JL, Loscalzo J, editors. Harrison´s Principles of Internal Medicine. Primary and Metastatic Tumors of the Nervous System. 19th ed., Vol. 118. New York: McGraw Hill Education Medical; 2015. p. 598-607.

  2. Ostrom QT, Gittleman H, Fulop J, et al. CBTRUS statistical report: primary brain and central nervous system tumors diagnosed in the United States in 2008-2012. Neuro Oncol. 2015;17 Suppl 4:41-462.

  3. Ostrom QT, Gittleman H, Liao P, et al. CBTRUS statistical report: primary brain and central nervous system tumors diagnosed in the United States in 2007-2011. Neuro Oncol. 2014;16 Suppl 4:41-63.

  4. Ostrom QT, Gittleman H, Xu J, et al. CBTRUS statistical report: primary brain and other central nervous system tumors diagnosed in the United States in 2009-2013. Neuro Oncol. 2016; 18:51-575.

  5. Wrensch M, Minn Y, Chew T, Bondy M, Berger MS. Epidemiology of primary brain tumors: current concepts and review of the literature. Neuro Oncol. 2002;4:278-99.

  6. Forsyth PA, Posner JB. Headaches in patients with brain tumors: a study of 111 patients. Neurology. 1993;43:1678-83.

  7. Pace A, Bove L, Innocenti P, et al. Epilepsy and gliomas: incidence and treatment in 119 patients. J Exp Clin Cancer Res. 1998; 17:479-82.

  8. Çetin ÖE, Ìsler C, Uzan M, Özkara Ç. Epilepsy-related brain tumors. Seizure. 2017;44:93-7.

  9. Naser RK, Hassan AA, Shabana AM, Omar NN. Role of magnetic resonance spectroscopy in grading of primary brain tumors. Egypt J Radiol Nucl Med. 2016;47:577-84.

  10. Lopez-Gonzalez, Sotelo J. Brain tumors in Mexico: characteristics and prognosis of glioblastoma. Surg Neurol. 2000;53:157-62.

  11. Alifieris C, Trafalis DT. Glioblastoma multiforme: pathogenesis and treatment. Pharmacol Ther. 2015;152:63-82.

  12. Louis DN, Ohgaki H, Wiestler OD, et al. The 2007 WHO classification of tumours of the central nervous system. Acta Neuropathol. 2007;114:97-109.

  13. Anaya-Delgadillo G, Juambelz-Cisneros PP, Fernández-Alvarado B, Pazos-Gómez F, Velasco-Torre A, Revuelta-Gutiérrez R. Prevalence of central nervous system tumors and histological identification in the operated patient: 20 years of experience. Cir Cir. 2016;84:447-53.

  14. Dolecek TA, Propp JM, Stroup NE, Kruchko C. CBTRUS statistical report: primary brain and central nervous system tumors diagnosed in the United States in 2005-2009. Neuro Oncol. 2012;14 Suppl 5:51-49.

  15. Nakamura H, Makino K, Yano S, Kuratsu J, Kumamoto Brain Tumor Research Group. Epidemiological study of primary intracranial tumors: a regional survey in Kumamoto prefecture in southern japan--20-year study. Int J Clin Oncol. 2011; 16:314-21.

  16. Ramos-Clason EC, Tuñón-Pitalua MC, Rivas-Muñoz FA, Veloza- Cabrera LA. Primary central nervous system tumours reported in cartagena, 2001-2006. Rev Salud Publica (Bogota). 2010; 12:257-67.

  17. Yanagihara TK, Lee A, Wang TJC. Quantitative analysis of the spatial distribution of metastatic brain lesions. Tomography. 2017;3:16-22.

  18. Shonka N, Venur VA, Ahluwalia MS. Targeted treatment of brain metastases. Curr Neurol Neurosci Rep. 2017;17:37.

  19. Duong LM, McCarthy BJ, McLendon RE, et al. Descriptive epidemiology of malignant and nonmalignant primary spinal cord, spinal meninges, and cauda equina tumors, united states, 2004- 2007. Cancer. 2012;118:4220-7.

  20. Gilbert RW, Kim JH, Posner JB. Epidural spinal cord compression from metastatic tumor: diagnosis and treatment. Ann Neurol. 1978;3:40-51.

  21. Payer S, Mende KC, Westphal M, Eicker SO. Intramedullary spinal cord metastases: an increasingly common diagnosis Neurosurg Focus. 2015;39:E15.

  22. Lee CH, Jung KW, Yoo H, Park S, Lee SH. Epidemiology of primary brain and central nervous system tumors in Korea. J Korean Neurosurg Soc. 2010;48:145-52.




2020     |     www.medigraphic.com

Mi perfil

C?MO CITAR (Vancouver)

Rev Invest Clin. 2018;70