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2018, Number 3

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Dermatología Cosmética, Médica y Quirúrgica 2018; 16 (3)

Drug Reaction with Eosinophilia and Systemic Symptoms and Eosinophlic Pneumonia Associated to Lamotrigine. Case Report

Salazar JJ, León-Quintero GI, García V, Hernández D, Salazar E, de la Cabada J
Full text How to cite this article

Language: Spanish
References: 12
Page: 208-211
PDF size: 169.00 Kb.


Key words:

Drug rash with eosinophilia and systemic symptoms, DRESS, methylprednisolone, lamotrigine.

ABSTRACT

Drug rash with eosinophilia and systemic symptoms (dress) is a rare condition caused by multiple drugs. Its characterized by skin and systemic compromise and potentially lethal. We report a 16-year-old female who developed DRESS after the administration of lamotrigine. This particular case presented pulmonary involvement and accurate response to systemic corticosteroids.


REFERENCES

  1. Husain Z, Reddy BY y Schwartz RA, DRESS syndrome: Part I. Clinical perspectives, J Am Acad Dermatol 2013; 68(5):693-708.

  2. Graña D, Botta C, Núñez M, Perendones M y Carlos D, Síndrome de DRESS. A propósito de tres casos clínicos y revisión de la literatura, Arch Med Interna 2015; 37(2):68-73.

  3. Correa de Castro B, Paniago AM, Takita LC y Hans-Filho G, Drug reaction with eosinophilia and systemic symptoms: a clinicopathological study of six cases at a teaching hospital in midestern Brazil, Int J Dermatol 2016; 55(3):328-34.

  4. Osuna Osuna J, Toledo Bahena ME, Valencia Herrera A, Ramírez Cortés E y Mena Cedillos C, Reacción por drogas con eosinofilia: síndrome DRESS, un gran simulador, DCMQ 2013; 11(2):142-47.

  5. Miller M, Lam B, Sutton A, Crew A y Peng D, Drug reaction with eosinophilia and systemic symptoms (dress): a retrospective study of 29 cases evaluating ResgiSCAR criteria and treatment, J Am Acad Dermatol 2017; 76(6): suplement 1 AB106

  6. Ocampo-Garza J, Ocampo-Garza S, Martínez-Villareal JD, Barbosa- Moreno LE, Guerrero-González GA y Ocampo-Candiani J, Reacción a drogas con eosinofilia y síntomas sistémicos (síndrome de DRESS). Estudio retrospectivo de nueve casos, Rev Med Chile 2015; 143:577-83.

  7. Sultan SJ, Sameen F y Ashraf M, Drug reaction with eosinophilia and systemic symptoms: manifestations, treatment, and outcome in 17 patients, Int J Dermatol 2015; 54(5):537-41.

  8. Roujeau JC y Dupin N, Virus reactivation in drug reaction with eosinophilia and systemic symptoms (DRESS). Results from a strong drugspecific immune response, J Allergy Clin Immunol Pract 2017; 5(3):811-2.

  9. Liang J, Qu H, Wang X, Liu L, Tu P y Wang M, Drug reaction with eosinophilia and systemic symptoms assoaciated with reactivation of Epstein-Barr virus and/or cytomegalovirus leading to hemophagocytic syndrome in one of two patients, Ann Dermatol 2018; 30(1):71-4.

  10. Young-Tsu Ch, Che-Wen Y y Chia-Yu Ch, Drug reaction with esosinophilia and systemic symptoms (DRESS): and interplay among drugs, viruses and immune system, Int J Mol Sci 2017; 18(6):1243-64.

  11. Funk-Bretano E, Duong T, Bouvresse S, Bagot M, Wolkenstein P, Roujeau JC et al., Therapeutic management of DRESS: a retrospective study of 38 cases, J Am Acad Dermatol 2015; 72(2):246-52.

  12. Chen Y, Chang Ch, Cho Y, Chiu H y Chu Ch, Long-term sequelae of drug reaction with eosinophilia and systemic symptoms: a restrospective cohort study from Taiwan, J Am Acad Dermatol 2013; (3):459-65.




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Dermatología Cosmética, Médica y Quirúrgica. 2018;16