Aguilar-Salinas CA, Tussié-Luna T, Almeda-Valdés P

Language: English
References: 7
Page: 209-210
PDF size: 53.14 Kb.

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Research in lipoprotein metabolism has been a highly successful endeavor1. This topic has been among the primary targets for the application of the newest research techniques, leading up to the rapid development of innovative products, international consortia, and multidisciplinary interventions2. In addition, translation of basic science into clinical practice has been very efficient. The high prevalence of lipid disorders, the large contribution of these conditions in the pathogenesis of cardiovascular morbidity, and the availability of potent lipid-lowering agents have been determinants of the large impact of these studies in our societies.

REFERENCES

1. Jeff JM, Peloso GM, Do R. What can we learn about lipoprotein metabolism and coronary heart disease from studying rare variants? Curr Opin Lipidol. 2016;27:99-104.

2. Ellis KL, Hooper AJ, Burnett JR, Watts GF. Progress in the care of common inherited atherogenic disorders of apolipoprotein B metabolism. Nat Rev Endocrinol. 2016;12:467-84.

3. Danchin N, Almahmeed W, Al-Rasadi K, et al. Achievement of low-density lipoprotein cholesterol goals in 18 countries outside Western Europe: The international choLesterol management practice study (ICLPS). Eur J Prev Cardiol. 2018;25:1087-94.

4. Ripatti P, Rämö JT, Söderlund S, et al. The Contribution of GWAS loci in familial dyslipidemias. PLoS Genet. 2016;12:e1006078.

5. Singh SA, Andraski AB, Pieper B, et al. Multiple apolipoprotein kinetics measured in human HDL by high-resolution/accurate mass parallel reaction monitoring. J Lipid Res. 2016;57:714-28.

6. Chait A, Goldberg I. Treatment of dyslipidemia in diabetes: recent advances and remaining questions. Curr Diab Rep. 2017;17:112.

7. Hegele RA, Ginsberg HN, Chapman MJ, et al. The polygenic nature of hypertriglyceridaemia: implications for definition, diagnosis, and management. Lancet Diabetes Endocrinol. 2014;2:655-66.