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Ginecología y Obstetricia de México

Federación Mexicana de Ginecología y Obstetricia, A.C.
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2018, Number 09

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Ginecol Obstet Mex 2018; 86 (09)

Diagnostic and therapeutic approach of febrile syndrome in patients after total abdominal hysterectomy

Álvarez-Cabrera MC, Carranza-Lira S
Full text How to cite this article

Language: Spanish
References: 12
Page: 584-589
PDF size: 270.95 Kb.


Key words:

Fever, Total abdominal hysterectomy, Surgical time, Leukocytes, Hemoglobin.

ABSTRACT

Objective: To describe the paraclinical tests and the medications indicated to revert the fever in the patients who had it in the following 48 hours after the total abdominal hysterectomy.
Materials and Methods: Observational, cross-sectional, retrospective, descriptive, open, uncontrolled study consisting of the review of the records of patients with total abdominal hysterectomy. Patients scheduled in the outpatient clinic were included only for total abdominal hysterectomy with fever in the first 48 hours post-intervention. According to the distribution of each variable, parametric and non-parametric statistics, Wilcoxon test and proportional differences were used.
Results: Of 181 hysterectomies performed, 34 patients had fever in the first 48 hours after surgery (19%). The surgical time was 116.7 ± 29.4 minutes and the bleeding were 498.5 ± 221.4 mL. The leukocytes were increased by 30% after the detection of fever with respect to the presurgical values; hemoglobin decreased by 14%. The general urine test was reported altered in 29%. The first febrile peak reached 38.6 ± 0.5 °C at 32.8 ± 8.3 hours after surgery with a persistence of 1.5 ± 0.9 days. 44% of patients received an antibiotic after evidence of infectious cause fever; the most indicated were: nitrofurantoin and ciprofloxacin.
Conclusions: Given the evidence of the first febrile peak, it is important to perform two laboratory tests: blood count and urinalysis, and based on the reports, decide whether the prescription of antibiotics is necessary.


REFERENCES

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  2. Dicker RC, et al. Complications of abdominal and vaginal hysterectomy among women of reproductive age in the United States. The Collaborative Review of Sterilization. https://doi.org/10.1016/0002-9378(82)90362-3

  3. Lesperance R, et al. Early postoperative fever and the "routine" fever work-up: results of a prospective study. https://doi.org/10.1016/j.jss.2010.03.009

  4. Wortel CH, et al. Interleukin-6 mediates host defense responses nduced by abdominal surgery. Surgery 1993;114(3):564-70.

  5. Lachiewicz MP, et al. Infection prevention and evaluation of fever after laparoscopic hysterectomy. doi: 10.4293/ JSLS.2015.00065

  6. Pothinam S, et al. Febrile and infectious morbidity after abdominal hysterectomy at Srinagarind Hospial. J Med Assoc Thai 1992;75(3):178-83.

  7. Mittendorf R, et al. Avoiding serious infections associated with abdominal hysterectomy: A meta-analysis of antibiotic prophylaxis. https://doi.org/10.1016/0002- 9378(93)90266-L

  8. Shapiro M, et al. Risk factors for infection at the operative site after abdominal or vaginal hysterectomy. DOI: 10.1056/ NEJM198212303072701

  9. Duff P. Antibiotic prophylaxis for abdominal hysterectomy. Obstet Gynecol 1982;60(1):25-29.

  10. Rybak EA, et al. Explained compared with unexplained fever in postoperative myomectomy and hysterectomy patients. doi: 10.1097/AOG.0b013e31816baea8.

  11. Schwandt A, et al. Prospective analysis of a fever evaluation algorithm after major gynecologic surgery. DOI: 10.1067/ mob.2001.115227

  12. Chirdchim W, et al. Risk factors for febrile morbidity after abdominal hysterectomy in a university hospital in Thailand. DOI:10.1159/000115843




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Ginecol Obstet Mex. 2018;86