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Anales de Otorrinolaringología Mexicana

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2018, Number 3

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Otorrinolaringología 2018; 63 (3)

Effect of muscle relaxant on transoperatory bleeding and postoperatory laryngospasm in adenotonsillectomy

Horcasitas-Pous R, Contreras-Núñez L, Veliz-Flores F, Flores-Montoya J
Full text How to cite this article

Language: Spanish
References: 10
Page: 102-106
PDF size: 275.44 Kb.


Key words:

Tonsillectomy, Rocuronium, Sugammadex.

ABSTRACT

Objective:To determine if the use of muscular relaxant (rocuronium) and sugammadex decreases the laryngospasm and transoperative bleeding in patients subjected to an adenotonsillectomy.
Material and Method: A randomized, controlled, prospective and comparative clinical test was done in patients from 2 to 13 years old, subjected to an adenotonsillectomy as an elective manner from August 2015 to June 2016 at the Hospital Infantil de Chihuahua, divided into two groups: one group was administered rocuronium and sugammadex; the other group was not administered any muscular relaxant.
Results: There were done 50 surgeries. It was obtained that the average intraoperative bleeding in the group without relaxant was of 71.6 cc, while the one in group with relaxant was of 81.6 cc (p = 0.698); p 0.05 was not significant for the study; however, in the group without relaxant 8 patients (32%) had laryngospasm vs the group with relaxant: 3 (12%), with a p value of 0.01708 (p ‹ 0.05), being statistically significant. Average surgical time of groups with and without relaxant was 15 and 13 minutes, respectively (p = 0762).
Conclusion: The administration of rocuronium and concomitant sugammadex to revert the muscle relaxation on tonsillectomy decreases the laryngospam and can alter the transoperative bleeding.


REFERENCES

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  8. Suzuki T, Kitajima O, Ueda K, Kato J, Ogawa S. Reversibility of rocuronium-induced profound neuromuscular block with sugammadex in younger and older patients. Br J Anaesth 2011 Apr;106(6); 823-826.

  9. Gupta A, Kaur R, Malthora R, Kale S. Comparative evaluation of different doses of propofol, preceded by fentanyl on the intubating conditions and the pressor response during tracheal intubation without muscle relaxants. Pediatr Anesth 2006;16(4):399-405.

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Otorrinolaringología. 2018;63