2018, Number 4
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ABSTRACTNowadays, cancer have increased; non-Hodgkin lymphomas in Mexico represent the second cause of hematological malignancies, in addition, there are methods of staging the disease, risk and an approach to gene expression profiles by immunohistochemistry that have important implications in diagnosis, prognosis and treatment. Over time, the diagnostic instruments, equipment and techniques have been perfected, which allows the optimization of the results to establish the basic measures to subclassify the lymphomas by histological strain, phenotype B or T, degree of maturation, replication index as well as molecular characteristics and even differentiation algorithms. Once the variety and subtype of lymphoma are defined, there are other issues for the clinician, among which are the sites involved and with these sites, the optimal classification system, whatever it is, which allows optimizing the final results and predicting the possible outcomes in survival is this group of patients. The target of this document is to summarize the general characteristics to be considered in patients with non- Hodgkin lymphoma at the beginning of treatment; however, it should be remembered that advances in this medical area may generate controversies with this review and must dominate clinical reasoning and the medicine based on evidence in favor of the clinical benefit of the patients.
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