Solomón CMT, Ardisana SE, Cabrera GE

Language: Spanish
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ABSTRACT

Objective: To assess the controversies about the surgical treatment of high malignancy degree lobar gliomas in adults.
Acquisition of evidences: They used the published research in PubMed and Scielo search engines in the last 5 years (2013-2018). Those documents containing contradictory information were taken into account.
Results: Multimodal treatment is the alternative that has shown the best results in the survival of patients with high malignancy grade gliomas. In most patients, surgery is the most important procedure in the treatment. There are three controversies regarding the surgical behavior of high malignancy degree gliomas: craniotomy versus a single trephine; assessment of the degree of tumor resection, and surgery versus observational medical treatment. A maximum tumor resection should be indicated, with no neurological defects addition. The use of new technologies is recommended to achieve wide and safe resections. The biopsy is indicated in well selected patients and tumors.
Conclusions: Multimodal treatment is the general guideline for patients with high malignancy grade gliomas. However, in the molecular era, personalized treatment is necessary.