Sanz PNJ, Fernández SPL, Fernández SFA, Fernández SPA

Language: Spanish
References: 0
Page: 399-410
PDF size: 291.75 Kb.

ABSTRACT

Introduction: among most frequent malignant breast tumors, ductal carcinoma has prevailed. Its malignancy histological level has become the prognosis factor. However, histopathological abnormalities like intra and peritumoral inflammatory infiltrates intensity, still require serious studies.
Objectives: to determine intra and peritumoral inflammatory infiltrates intensity, and to identify their relation to malignancy histological levels.
Methods: a case series study with 392 infiltrating ductal carcinoma diagnosed biopsies, at Lenin Hospital Pathological Anatomy Department, from 2011 to 2015; in which presence and intensity of intratumoral, and peritumoral inflammatory infiltrates, and malignancy histological level, were found.
Results: breast tumors were differentiated up to 68.1%. Intra and peritumoral lights inflammatory infiltrate prevailed, with 44.9% and 55.4% each. Well differentiated lights inflammatory infiltrated tumors reached 84.6%. Moderate differentiated tumors were moderate infiltrated, up to 47.2%; and poor diferentiated with severe inflamatory infíltrate, presented 41.7%. Among well differentiated tumors, peritumoral light inflamatory infiltrate revealed 92.3%. Those poor differentiated were only 48.3% positively related.
Conclusions: intra and peritumoral light intensity inflammatory infiltrate was the most frequent, considered as the potential prognosis factor, because of its directly proportional relationship with malignancy histological level.