Ortega TYY, Armas RNB, Llanes EJR, Peñafiel CJ, Valdés MA, Jerez CAM, Cabrera RJO

Language: Spanish
References: 0
Page:
PDF size: 409.62 Kb.

ABSTRACT

Introduction: The reduction of cholesterol with statins prevents cardiovascular events.
Objectives: To determine the reduction of cholesterol linked to low density lipoproteins with statins and its effect on the presence of adverse cardiovascular events.
Methodology: Descriptive, ambispective study. Universe: 827 patients with indication of statins who attended the follow-up six months after starting treatment. Sample: 181 patients.
Variables: Age, sex, total cholesterol, LDL cholesterol, triglycerides, reduction of total cholesterol, LDL cholesterol and triglycerides, adverse cardiovascular event.
Results: 89.5% of patients achieved a reduction in LDL-C levels, followed in order of frequency by total cholesterol (it was reduced by 50% in 69.1% of patients), while the triglycerides showed lower reduction, with 45.9%. Adverse events were 1.32 times higher in those subjects in whom total cholesterol was not reduced and 2.01 times higher in those who did not have LDL-C reduction. The reduction in triglycerides was higher in the group with adverse events (58.5% versus 51.7%) (the differences were not significant).
Conclusions: The levels of total cholesterol, triglycerides and LDL-C, six months after the end of the treatment with statins, were significantly reduced with respect to the start of treatment. The reduction of total cholesterol and LDL-C had a protective effect in the appearance of adverse events.